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TranscriptomicsValidation of rapid embryo tracking using cell-free fetal DNA enriched from maternal circulation at 9 weeks gestation
Embryo DNA fingerprinting represents an important tool for tracking embryo-specific outcomes after multiple embryo transfer during IVF. The situation in which 2 embryos are transferred and only one implants represents a unique opportunity for the most well-controlled comparison of competent and inc...
ORGANISM(S): Homo sapiens 
2011-04-14 | E-GEOD-26404 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of diabetic neuropathy in dorsal root ganglia from streptozotocin-diabetic male wistar rats over the first 8 weeks of diabetes
A study of diabetic neuropathy in dorsal root ganglia from streptozotocin-diabetic male wistar rats over the first 8 weeks of diabetes
ORGANISM(S): Rattus norvegicus 
2006-12-10 | E-MEXP-515 | biostudies-arrayexpress
MetabolomicsDiagnostic utility of clinicodemographic, biochemical and metabolite variables to identify viable pregnancies in a symptomatic cohort during early gestation.

Study question: Can a novel machine learning pipeline create predictive models that identify a composite biomarker to differentiate live normally sited pregnancies (LNSP) from non-viable pregnancies in women presenting with pain and/or bleeding in early gestation?

Summary answer: Serum met...

2025-08-14 | MTBLS6219 | MetaboLights
TranscriptomicsTranscription profiling of mouse lung tissue after exposure to mainstream tobacco smoke
We have examined the impact of subchronic levels of tobacoo smoke on murine lungs. We have used high density DNA microarray and analysed lung tissues from mice exposed to mainstream tobacco smoke (MTS). Our results reveal induction of inflammatory cytokine interleukin-6 (IL-6) and its antagonist sup...
ORGANISM(S): Mus musculus 
2009-09-18 | E-GEOD-12930 | biostudies-arrayexpress
TranscriptomicsGenome-wide changes in subcutaneous adipose tissue expression in HIV negative adults after 2 weeks of zidovudine or stavudine with lamivudine.
As controversy remains as to the exact mechanisms by which the thymidine-analogue nucleoside reverse transcriptase inhibitors, zidovudine (AZT) and stavudine (d4T) induce subcutaneous adipose tissue toxicity, we used microarrays to dentify patterns of gene expression in human subcutaneous adipose ti...
ORGANISM(S): Homo sapiens 
2012-03-15 | E-GEOD-34302 | biostudies-arrayexpress
TranscriptomicsInvestigation of placental gene expression in obese women exposed to Metformin during pregnancy
Maternal obesity in pregnancy is associated with increased birth-weight, obesity and premature mortality in adult offspring. The Effect of Metformin on Maternal and Fetal Outcomes in Pregnant Obese Women (EMPOWaR) trial was a randomised, double-blind, placebo-controlled trial carried out to determin...
ORGANISM(S): Homo sapiens 
2019-01-31 | E-MTAB-6418 | biostudies-arrayexpress
TranscriptomicsAccurate prediction and validation of response to endocrine therapy in breast cancer
Purpose Aromatase inhibitors (AIs) have an established role in breast cancer treatment. Response rates are only 50-70% in the neoadjuvant setting and lower in advanced disease. Accurate biomarkers are urgently needed to predict response in these settings and to determine which individuals will bene...
ORGANISM(S): Homo sapiens 
2015-07-06 | E-GEOD-59515 | biostudies-arrayexpress
TranscriptomicsComprehensive characterization and RNA-Seq profiling of the HD-Zip transcription factor family in soybean (Glycine max) during dehydration and salt stress
Background The homeodomain leucine zipper (HD-Zip) transcription factor family is one of the largest plant specific superfamilies, and includes genes with roles in modulation of plant growth and response to environmental stresses. Many HD-Zip genes are characterized in Arabidopsis (Arabidopsis thal...
ORGANISM(S): Glycine max 
2014-11-01 | E-GEOD-57252 | biostudies-arrayexpress
TranscriptomicsInvestigation of placental DNA methylation in obese women exposed to Metformin during pregnancy
Maternal obesity in pregnancy is associated with increased birth-weight, obesity and premature mortality in adult offspring. The Effect of Metformin on Maternal and Fetal Outcomes in Pregnant Obese Women (EMPOWaR) trial was a randomised, double-blind, placebo-controlled trial carried out to determin...
ORGANISM(S): Homo sapiens 
2018-11-01 | E-MTAB-6421 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse striatum from 12 weeks-old R6/2 vs. control animals
This SuperSeries is composed of the following subset Series:; GSE9803: Striatal gene expression data from 12 weeks-old R6/2 mice and control mice (set 1); GSE9804: Striatal gene expression data from 12 weeks-old R6/2 mice and control mice (set 2) Experiment Overall Design: Refer to individual Series
ORGANISM(S): Mus musculus 
2008-06-16 | E-GEOD-9857 | biostudies-arrayexpress
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