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ProteomicsQuantitative phosphoproteomics study for assessing rodent thyroid toxicity
Here, we aimed to apply a TMT based quantitative phosphoproteomics approach to investigate rodent thyroid toxicity. For this purpose, male Wistar rats have been exposed to a direct (6-propyl-2-thiouracil, PTU) and an indirect (phenytoin) thyroid toxicant, respectively. Thereby, two doses (low:5ppm f...
ORGANISM(S): Rattus norvegicus (Rat) 
2024-10-25 | PXD030254 | Pride
Phosphoproteomics  liver  tmt Thyroid toxicity  ptu Phenytoin 
UnknownRural disparities in surgical care from gynecologic oncologists among Midwestern ovarian cancer patients.
Not available
S-EPMC7869694 | biostudies-literature
UnknownSports-Related Injuries in Deaf Competitive Squad Athletes-Results of a Retrospective Self-Assessment.
Not available
S-EPMC11861969 | biostudies-literature
TranscriptomicsCircadian Liver Gene Expression in Animals on Normal Chow or High Fat Diet
Circadian and metabolic processes are codependent. This experiment was designed to understand how a high fat diet affects circadian gene expression in the liver. Circadian gene expression in the liver is necessary for energy balance. Animals consuming normal chow or high fat diet (60% kcal from fat)...
ORGANISM(S): Mus musculus 
2013-12-19 | E-GEOD-52333 | biostudies-arrayexpress
ProteomicsTissue proteome of visceral, subcutaneous and brown adipose as well as liver tissues in an obese mouse model after dietary exposure to the emerging phthalate substitute DINCH
Here, we analysed the global proteome of visceral, subcutaneous and brown adipose as well as liver tissues in a C57BL/6J mouse model of diet-induced obesity, following dietary exposure to 1,2-cyclohexane dicarboxylic acid diisononyl ester (DINCH). This study includes data on male and female mice, as...
ORGANISM(S): Mus musculus (Mouse) 
2025-02-03 | PXD054970 | Pride
Tissue proteomics Obesity Dinch Mouse 
TranscriptomicsEstablishment of a novel model to assess the function of proteins under in vivo conditions
We established a novel model to assess the function of proteins under in vivo conditions. The model relies on the expansion of HEK293 cells in immunodeficient NOD.Scid mice. To validate the novel model, we performed microarray gene expression profiling of NOD.Scid-expanded HEK293 cells relative to c...
ORGANISM(S): Homo sapiens 
2009-10-26 | E-GEOD-18739 | biostudies-arrayexpress
UnknownEconomic burden of dengue in Indonesia.
Not available
S-EPMC6343936 | biostudies-literature
TranscriptomicsOmeprazole stimulated gene expression in rats
Omeprazole stimulated gene expression in rats Samples and RNA preparation: The series is composed of 9 hybridizations for analysis of differentially expressed genes in the gastric mucosa of omeprazole dosed vs. control rats. Nine rats (200-250 g) were given (by gavage) 400 micromol/kg of the proton ...
ORGANISM(S): Rattus norvegicus 
2010-06-05 | E-GEOD-1808 | biostudies-arrayexpress
Unknown1089. Use of a Whole-Body Quantitative System Pharmacology Physiologically-Based Pharmacokinetic (QSP/PBPK) Model to Support Dose Selection of ADG20: an Extended Half-Life Monoclonal Antibody Being Developed for the Prevention of Coronavirus Disease (COVID-19)
Not available
S-EPMC8644371 | biostudies-literature
UnknownPhase I trial and pharmacokinetic study of lexatumumab in pediatric patients with solid tumors.
Not available
S-EPMC3494837 | biostudies-literature
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