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ProteomicsTHP-1 cells treated with plasticizer DINCH and metabolite MINCH
Since 2008, the consumption of the plasticizer bis (2-ethylhexyl) phthalate (DEHP) in the manufacture of plastic products has been restricted due to several adverse health effects. 1,2-cyclohexanedicarboxylic acid diisononyl ester (DINCH) is increasingly used as a harmless substituent for DEHP. Howe...
ORGANISM(S): Homo sapiens (Human) 
2022-01-10 | PXD027744 | Pride
Endocrine disruption Plasticizers Minch Dinch 
ProteomicsTissue proteome of visceral, subcutaneous and brown adipose as well as liver tissues in an obese mouse model after dietary exposure to the emerging phthalate substitute DINCH
Here, we analysed the global proteome of visceral, subcutaneous and brown adipose as well as liver tissues in a C57BL/6J mouse model of diet-induced obesity, following dietary exposure to 1,2-cyclohexane dicarboxylic acid diisononyl ester (DINCH). This study includes data on male and female mice, as...
ORGANISM(S): Mus musculus (Mouse) 
2025-02-03 | PXD054970 | Pride
Tissue proteomics Obesity Dinch Mouse 
ProteomicsEffects of DINCH and MINCH exposure on the proteome of differentiating primary human stromal vascular fraction cells
Here, we evaluated the molecular effects of 10 nM and 10 µM DINCH and MINCH exposure on the proteome profiles of differentiating human primary SVF cells. The SVF cells derived from the subcutaneous adipose tissue of donors undergoing aesthetic surgery at abdomen, leg or back. The dataset comprised m...
ORGANISM(S): Homo sapiens (Human) 
2025-08-05 | PXD059419 | Pride
Human stromal vascular fraction Adipogenesis Dinch Subcutaneous adipose tissue Minch 
ProteomicsEffects of dietary DINCH exposure on the proteome, phosphoproteome and acetylome of adipose tissue of a murine diet induced model of obesity
Here, we evaluated the molecular effects of dietary DINCH exposure, on the proteome, phosphoproteome and acetylome profiles of visceral and subcutaneous adipose tissue in a model of diet-induced obesity in male and female C57BL/6N mice. This study includes data on visceral and subcutaneous adipose t...
ORGANISM(S): Mus musculus (Mouse) 
2025-08-05 | PXD059421 | Pride
Acetylome Phosphoproteome C57bl/6n mice Subcutaneous adipose tissue Diet induced obesity Proteome Visceral adipose tissue Dinch 
UnknownBiomonitoring of emerging DINCH metabolites in pregnant women in charleston, SC: 2011-2014.
Not available
S-EPMC7670082 | biostudies-literature
UnknownEnvironmental exposure to the plasticizer 1,2-cyclohexane dicarboxylic acid, diisononyl ester (DINCH) in U.S. adults (2000-2012).
Not available
S-EPMC4554753 | biostudies-literature
UnknownEffect of prenatal DINCH plasticizer exposure on rat offspring testicular function and metabolism.
Not available
S-EPMC5593853 | biostudies-literature
UnknownConcentrations of phthalates and DINCH metabolites in pooled urine from Queensland, Australia.
Not available
S-EPMC7957829 | biostudies-literature
UnknownAssociation of in utero exposure to phthalate and DINCH metabolites with placental DNA methylation.
Not available
S-EPMC12696147 | biostudies-literature
UnknownThe Emerging Plasticizer Alternative DINCH and Its Metabolite MINCH Induce Oxidative Stress and Enhance Inflammatory Responses in Human THP-1 Macrophages.
Not available
S-EPMC8466537 | biostudies-literature
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