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Proteomicsβ-Hydroxybutyrylation in Diabetic Cardiomyopathy
Diabetic cardiomyopathy (DCM) is characterized by metabolic remodeling and energetic stress independent of coronary artery disease. Increased reliance on fatty acid and ketone body metabolism has been observed in DCM, but the regulatory mechanisms linking altered substrate utilization to myocardial ...
ORGANISM(S): Mus musculus (Mouse) 
2026-03-26 | PXD066713 | Pride
Diabetic cardiomyopathy  β-hydroxybutyrylation (kbhb)  metabolic remodeling  ketone body metabolism  mitochondrial regulation 
ProteomicsLactylation in Diabetic Cardiomyopathy
Lysine lactylation (Kla), is a newly found post-translational modification that has been found to be involved in the pathogenesis of many diseases. However, the specific effect of protein lactylation has not been reported on the development of diabetic cardiomyopathy (DCM). Here, the purpose of this...
ORGANISM(S): Mus musculus (Mouse) 
2026-05-25 | PXD067368 | Pride
Lactylome  proteome  protein lactylation  diabetic cardiomyopathy 
TranscriptomicsTranscriptome analysis reveals global regulation in response to CO2 supplementation in oleaginous microalga Coccomyxa subellipsoidea C-169
The microalga Coccomyxa subellipsoidea C-169 possesses some features that may be valuable for lipid production, and, as demonstrated in this study, can be greatly induced to produce a high amount of fatty acid by CO2 supplementation. Here we have compared the transcriptome of air group (AG, cells cu...
ORGANISM(S): Coccomyxa subellipsoidea C-169 
2016-05-17 | E-GEOD-76638 | biostudies-arrayexpress
ProteomicsComparative analysis of serum proteins between hepatitis B virus genotype B and C infection DIA-based quantitative proteomics
Hepatitis B virus (HBV) is an enveloped, coated, non-cytopathic and hepatotropic partially double-stranded DNA virus in the family Hepadnaviridae genus Orthohepadnavirus. Despite significant progress in the availability of safe vaccines and antiviral therapies against HBV, it still affects approxima...
ORGANISM(S): Homo sapiens (Human) 
2022-02-17 | PXD025968 | Pride
Serum proteins hbv genotype b and c infection dia-based quantitative proteomics 
ModelsWei2011_MLCactivationPathway_EndothelialPermeability
This model is from the article: An Integrated Mathematical Model of Thrombin-, Histamine-and VEGF-Mediated Signalling in Endothelial Permeability. Wei X, Han B, Zhang J, Liu X, Tan C, Jiang Y, Low B, Tidor B, Chen Y. BMC Syst Biol. 2011 Jul 15;5:112. ...
2005-01-01 | MODEL1102210000 | BioModels
UnknownTranscriptome Analysis Reveals Long Intergenic Non-Coding RNAs Contributed to Intramuscular Fat Content Differences between Yorkshire and Wei Pigs.
Not available
S-EPMC7084294 | biostudies-literature
GenomicsTranscription factor Ebf1 regulates differentiation stage-specific signaling, proliferative expansion and survival of B cells [EBF1]
Transcription factor Ebf1 is an important determinant of early B lymphopoiesis. To gain insight into differentiation stage-specific functions of Ebf1, we conditionally inactivated Ebf1. We found that Ebf1 is required for proliferation, survival and signaling of pro-B cells and peripheral B cell su...
ORGANISM(S): Mus musculus 
2012-04-02 | E-GEOD-35910 | biostudies-arrayexpress
UnknownEfficacy and safety of Jia Wei Bushen Yiqi formulas as an adjunct therapy to systemic glucocorticoids on acute exacerbation of COPD: study protocol for a randomized, double-blinded, multi-center, placebo-controlled clinical trial.
Not available
S-EPMC7468179 | biostudies-literature
MetabolomicsNon-invasive urinary metabolomic profiles discriminate biliary atresia from infantile hepatitis syndrome
INTRODUCTION: Neonatal cholestatic disorders are a group of hepatobiliary diseases occurring in the first 3 months of life. The most common causes of neonatal cholestasis are infantile hepatitis syndrome (IHS) and biliary atresia (BA). The clinical manifestations of the two diseases are ...
2019-06-25 | MTBLS689 | MetaboLights
ProteomicsProteome Analysis of Avian Metapneumovirus C Type infected Vero cells by iTRAQ coupled with LC-MS
To date, no study has been carried out to assess the protein profiles of aMPV/C-infected cells. In the present study, iTRAQ combined with LC-MS/MS was used to reveal the global proteomic changes occurring in Vero cells in response to aMPV/C infection for the first time and to help understand the mol...
ORGANISM(S): Cercopithecus aethiops (Green monkey) (Grivet) 
2020-04-03 | PXD017827 | Pride
Vero cells Lc-ms Ampv/c 
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