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UnknownMicrometer-scale transient ion transport for real-time pH assay in living rat brains.
Not available
S-EPMC8171349 | biostudies-literature
ProteomicsDDX5-sIL-36R in keratinocytes controls skin inflammation
The DEAD-box (DDX) proteins function in diverse cellular processes including RNA alternative splicing, and are linked to immune-mediated diseases. However, little is known about the roles of DDXs in skin inflammatory diseases. Here, we show that DDX5, one of the founding members of the DDX RNA helic...
ORGANISM(S): Homo Sapiens 
2020-09-09 | PXD021379 |
ProteomicsTranscriptome and iTRAQ proteomic analysis reveal the molecular mechanism of anti- Candida albicans action of trichoderma acid, a potent novel drug candidate
Candida albicans has become one of the main pathogens of fungal infection, which causes great threaten to human health. Hence, it is urgent to develop new anti- C. albicans drugs. A compound named as trichoderma acid was isolated from Trichoderma spirale , which showed stronger inhibitory effect tow...
ORGANISM(S): Candida Albicans 
2021-05-06 | PXD025834 |
ProteomicsPeptidomics and Quantitative Proteomics Analysis of Peptides from Ophiocordyceps sinensis
This project includes two parts of mass spectrometry-based omics analysis. First, peptidomics analysis was performed to identify endogenous free peptides from Ophiocordyceps sinensis. Second, quantitative proteomic analysis was applied to investigate the global protein expression changes in RAW 264....
ORGANISM(S): Mus Musculus 
2026-04-03 | PXD076647 |
ProteomicsInhibition of circulating glycocholic acid-regulated signaling potentiates immune checkpoint therapy in colorectal cancer
Serum bile acids (BAs) emerge as risk factors for cancer, but their roles in colorectal cancer (CRC) remain unclear. We show that glycocholic acid (GCA), a primary BA, is elevated in the serum of CRC patients. In a mouse CRC model, GCA promotes tumor programmed death-ligand 1 (PD-L1) expression in t...
ORGANISM(S): Mus <genus> 
2026-03-03 | PXD075127 |
ProteomicsSystematic discovery of linear ubiquitination mediated neo-protein-protein interactions across mouse tissues
HOIP truncations proteins GST-PUB, GST-NZF, GST-UBA and GST-RBR-LDD were purified, GST was used as a negative control. The tissue lysates from the C57BL/6 mice were incubated with glutathione-S-transferase (GST) beads which bound to the GST-HOIP truncation proteins beforehand. The pull-down componen...
ORGANISM(S): Mus Musculus 
2024-02-28 | PXD043322 |
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