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TranscriptomicsEvolution of mammalian miRNA genes
MicroRNAs (miRNAs) are major post-transcriptional regulators of gene expression, yet their origins and functional evolution in mammals remain little understood due to the lack of appropriate comparative data. Using RNA sequencing, we have generated extensive and comparable miRNA data for five organs...
ORGANISM(S): Macaca mulatta 
2012-10-01 | E-GEOD-40499 | biostudies-arrayexpress
TranscriptomicsCellular source and mechanisms of high transcriptome complexity in the mammalian testis (RNA-Seq organs)
Understanding  the  extent  of  genomic  transcription  and  its  functional  relevance  is  a  central  goal  in  genomics research. However, detailed genome‐wide investigations of transcriptome complexities in major mammalian organs  and  their  underlying  cellular  sources,  transcriptional  mec...
ORGANISM(S): Mus musculus 
2013-06-20 | E-GEOD-43721 | biostudies-arrayexpress
TranscriptomicsCellular source and mechanisms of high transcriptome complexity in the mammalian testis (RNA-Seq cells)
Understanding the extent of genomic transcription and its functional relevance is a central goal in genomics research. However, detailed genome€wide investigations of transcriptome complexities in major mammalian organs  and  their  underlying  cellular sources, transcriptional mechanisms, and func...
ORGANISM(S): Mus musculus 
2013-06-20 | E-GEOD-43717 | biostudies-arrayexpress
TranscriptomicsRNA-seq of 6 tissues from Monodelphis domestica to investigate the evolution of gene expression levels in mammalian organs
This experiment contains the subset of data corresponding to gray short-tailed opossum RNA-Seq data from experiment E-GEOD-30352 (http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-30352/), which goal is to understand the dynamics of mammalian transcriptome evolution. To study mammalian transcript...
ORGANISM(S): Monodelphis domestica 
2011-10-12 | E-MTAB-3719 | biostudies-arrayexpress
TranscriptomicsRNA-seq of 6 tissues from Homo sapiens to investigate the evolution of gene expression levels in mammalian organs
This experiment contains the subset of data corresponding to human RNA-Seq data from experiment E-GEOD-30352 (http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-30352/), which goal is to understand the dynamics of mammalian transcriptome evolution. To study mammalian transcriptome evolution at hig...
ORGANISM(S): Homo sapiens 
2011-10-12 | E-MTAB-3716 | biostudies-arrayexpress
TranscriptomicsRNA-seq of 6 tissues from Macaca mulatta to investigate the evolution of gene expression levels in mammalian organs
This experiment contains the subset of data corresponding to rhesus macaque RNA-Seq data from experiment E-GEOD-30352 (http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-30352/), which goal is to understand the dynamics of mammalian transcriptome evolution. To study mammalian transcriptome evoluti...
ORGANISM(S): Macaca mulatta 
2011-10-12 | E-MTAB-3717 | biostudies-arrayexpress
TranscriptomicsRNA-seq of 6 tissues from Mus musculus to investigate the evolution of gene expression levels in mammalian organs
This experiment contains the subset of data corresponding to mouse RNA-Seq data from experiment E-GEOD-30352 (http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-30352/), which goal is to understand the dynamics of mammalian transcriptome evolution. To study mammalian transcriptome evolution at hig...
ORGANISM(S): Mus musculus 
2011-10-12 | E-MTAB-3718 | biostudies-arrayexpress
TranscriptomicsRNA-seq of 6 tissues from 10 species to investigate the evolution of gene expression levels in mammalian organs
Changes in gene expression are thought to underlie many of the phenotypic differences between species. However, large-scale analyses of gene expression evolution were until recently prevented by technological limitations. Here we report the sequencing of polyadenylated RNA from six organs across ten...
ORGANISM(S): Gallus gallus 
2011-10-12 | E-GEOD-30352 | biostudies-arrayexpress
GenomicsCellular source and mechanisms of high transcriptome complexity in the mammalian testis (RRBS and ChIP-Seq)
Understanding  the  extent  of  genomic  transcription  and  its  functional  relevance  is  a  central  goal  in  genomics research. However, detailed genome‐wide investigations of transcriptome complexities in major mammalian organs  and  their  underlying  cellular  sources,  transcriptional  mec...
ORGANISM(S): Mus musculus 
2013-06-20 | E-GEOD-43719 | biostudies-arrayexpress
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