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TranscriptomicsPatterns of micro RNA expression characterize stages of human B-cell differentiation
Mature B-cell differentiation provides an important mechanism for the acquisition of adaptive immunity. Malignancies derived from mature B-cells constitute the majority of leukemias and lymphomas. These malignancies often maintain the characteristics of the normal B-cells that they are derived from,...
ORGANISM(S): Homo sapiens 
2009-03-16 | E-GEOD-15250 | biostudies-arrayexpress
TranscriptomicsMassively Parallel Sequencing Identifies the MicroRNA Transcriptome of Normal and Malignant Human B cells
Profiling of miRNA transcriptome in Human mature B cells from similar populations Profiling of miRNA transcriptome in Human Normal and Malignant B cells, 8 normal samples corresponding to Naïve, Germinal Center, Plasma and Memory B cells and 23 samples derived from B cell malignancy
ORGANISM(S): Homo sapiens 
2010-08-25 | E-GEOD-15229 | biostudies-arrayexpress
TranscriptomicsDeep Sequencing of the Small RNA Transcriptome of Normal and Malignant Human B cells Identifies Hundreds of Novel MicroRNAs: microarray analysis
A role for microRNAs has been recognized in nearly every biological system examined thus far. A complete delineation of their role must be preceded by the identification of all microRNAs present in any system. We elucidated the complete small RNA transcriptome of normal and malignant B cells through...
ORGANISM(S): Homo sapiens 
2010-08-26 | E-GEOD-22895 | biostudies-arrayexpress
TranscriptomicsLMP-420: a novel purine nucleoside analogue with potent cytotoxic effects for chronic lymphocytic leukemia cells
[original title] LMP-420: a novel purine nucleoside analogue with potent cytotoxic effects for chronic lymphocytic leukemia cells and minimal toxicity for normal hematopoietic cells. LMP-420 induces cytotoxicity and apoptosis to CLL cells in vitro without any negative effects to normal immune cells...
ORGANISM(S): Homo sapiens 
2011-02-01 | E-GEOD-20211 | biostudies-arrayexpress
TranscriptomicsDeep Sequencing of the Small RNA Transcriptome of Normal and Malignant Human B cells Identifies Hundreds of Novel MicroRNAs
This SuperSeries is composed of the following subset Series: GSE15229: Massively Parallel Sequencing Identifies the MicroRNA Transcriptome of Normal and Malignant Human B cells GSE22895: Deep Sequencing of the Small RNA Transcriptome of Normal and Malignant Human B cells Identifies Hundreds of Novel...
ORGANISM(S): Homo sapiens 
2010-08-25 | E-GEOD-22898 | biostudies-arrayexpress
UnknownPatterns of microRNA expression characterize stages of human B-cell differentiation.
Not available
S-EPMC2680365 | biostudies-literature
UnknownSET oncoprotein overexpression in B-cell chronic lymphocytic leukemia and non-Hodgkin lymphoma: a predictor of aggressive disease and a new treatment target.
Not available
S-EPMC3204732 | biostudies-literature
TranscriptomicsThe genetic landscape of mutations in Burkitt lymphoma
Burkitt lymphoma is characterized by deregulation of MYC, but the contribution of other genetic mutations to the disease is largely unknown. Here, we describe the first completely sequenced genome from a Burkitt lymphoma tumor and germline DNA from the same affected individual. We further sequen...
ORGANISM(S): Homo sapiens 
2013-07-01 | E-GEOD-48435 | biostudies-arrayexpress
UnknownDeep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs.
Not available
S-EPMC3012600 | biostudies-literature
TranscriptomicsAffymetrix SNP array data for NF1-associated glioma risk
We performed whole genome SNP profiling on DNA samples from 236 patients with NF1, 123 with glimoa tumors and 113 without; 117 females and 119 males, together with 29 control samples. To identify polymorphisms in human adenylate cyclase 8 (AC8) which correlate with glioma risk in NF1 in a sex-speci...
ORGANISM(S): Homo sapiens 
2015-02-20 | E-GEOD-62215 | biostudies-arrayexpress
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