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TranscriptomicsProtective unfolded protein response in human pancreatic beta cells transplanted into mice
Islet transplantation exposes beta cells to mild hyperglycemia and to the abnormal environment of the transplant site. These conditions may affect beta cells and induce the expression of genes involved in beta cell damage. Gene expression profile of human beta cells exposed to mild hyperglycemia by ...
ORGANISM(S): Homo sapiens 
2010-06-08 | E-GEOD-22097 | biostudies-arrayexpress
TranscriptomicsNeonatal beta cells lack the specialized metabolic phenotype of mature beta cells
Fetal and neonatal beta cells have poor glucose-induced insulin secretion and only gain robust glucose responsiveness several weeks after birth. This unresponsiveness may be due to a generalized immaturity of the metabolic pathways normally found in beta cells. Gene expression profile of neonatal (1...
ORGANISM(S): Rattus norvegicus 
2011-02-22 | E-GEOD-24790 | biostudies-arrayexpress
UnknownAntimicrobial Polyketide Metabolites from Penicillium bissettii and P. glabrum.
Not available
S-EPMC8746583 | biostudies-literature
UnknownA Revised Structure and Assigned Absolute Configuration of Theissenolactone A.
Not available
S-EPMC7587954 | biostudies-literature
UnknownThe factor of 10 in forensic DNA match probabilities.
Not available
S-EPMC7722394 | biostudies-literature
TranscriptomicsExpression Quantitative Trait Locus (eQTL) Mapping of Stage-specific Gene Expression in Progeny from a type I X III Genetic Cross of Toxoplasma gondii
The control of gene expression in Toxoplasma is not well understood. As we and others have shown, this organism does contain bipartite promoters that are sufficient to induce gene expression. This information can be used in downstream experiments to identify proteins that bind to experimentally co...
ORGANISM(S): Toxoplasma gondii 
2012-01-11 | E-GEOD-26558 | biostudies-arrayexpress
UnknownAntimicrobial Metabolites against Methicillin-Resistant Staphylococcus aureus from the Endophytic Fungus Neofusicoccum australe.
Not available
S-EPMC7922810 | biostudies-literature
UnknownTerrien, a metabolite made by Aspergillus terreus, has activity against Cryptococcus neoformans.
Not available
S-EPMC9586122 | biostudies-literature
TranscriptomicsGene expression analysis of OVCAR-3 and CDK2 resistant sublines
Cyclin E1 (CCNE1) is amplified in various tumor types including high-grade serous ovarian cancer where it is associated with poor clinical outcome. We have demonstrate that suppression of the Cyclin E1 partner kinase, CDK2, induces apoptosis in a CCNE1 amplicon-dependent manner. Little is known of m...
ORGANISM(S): Homo sapiens 
2013-09-01 | E-GEOD-48919 | biostudies-arrayexpress
TranscriptomicsLCM human islet beta cells
Fresh frozen sections of islets obtained by surgery were laser capture microdissected using autofluorescence to guide selection of beta cell areas of the islet. RNA was extracted and amplified with 2 rounds of T7 linear amplification. Two technical replicates were hybridized to Affymetrix U95Av2 arr...
ORGANISM(S): Homo sapiens 
2014-10-28 | E-MTAB-3042 | biostudies-arrayexpress
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