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UnknownStructural Insights into (Tere)phthalate-Ester Hydrolysis by a Carboxylesterase and Its Role in Promoting PET Depolymerization.
Not available
S-EPMC9764356 | biostudies-literature
TranscriptomicsTH-MYCN Mice with Caspase-8 Deficiency Develop Advanced Neuroblastoma with Bone Marrow Metastasis
Neuroblastoma, the most common extracranial pediatric solid tumor, is responsible for 15% of all childhood cancer deaths. Patients frequently present at diagnosis with metastatic disease, particularly to the bone marrow. Advances in therapy and understanding of the metastatic process have been lim...
ORGANISM(S): Mus musculus 
2013-05-22 | E-GEOD-42254 | biostudies-arrayexpress
TranscriptomicsExpression analysis of superior cervical ganglion from backcrossed TH-MYCN transgenic mice
Neuroblastoma susceptibility in TH-MYN mice is heavily influence by mouse strain background. We have combined linkage analysis of tumor susceptibility with expression QTL analysis of superior cervical ganglia (pure peripheral symptathetic nervous tissue) to identify genes underlying tumor formation...
ORGANISM(S): Mus musculus 
2015-01-30 | E-GEOD-59675 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of human CD14+ monocytes treated with cytokines IL-34 and mCSF to determine the effects on momocyte differentiation
IL-34 and mCSF effects on human monocyte differentiation
ORGANISM(S): Homo sapiens 
2011-05-18 | E-TABM-999 | biostudies-arrayexpress
GenomicsFundamental differences in promoter CpG island DNA hypermethylation between human cancer and genetically engineered mouse models of cancer [RRBS]
Genetic and epigenetic alterations are essential for the initiation and progression of human cancer. We previously reported that primary human medulloblastomas showed extensive cancer-specific CpG island DNA hypermethylation in critical developmental pathways. To determine whether genetically engine...
ORGANISM(S): Mus musculus 
2013-10-10 | E-GEOD-45341 | biostudies-arrayexpress
TranscriptomicsThe genetics of splicing in neuroblastoma
Regulation of mRNA splicing is a critical and tightly regulated cellular function, underlying the majority of proteomic diversity in our genomes. While disruption of this process is common in disease, the basic genetic complexity of alternative splicing in vivo remains poorly understood. To delinea...
ORGANISM(S): Mus musculus 
2015-04-03 | E-GEOD-55248 | biostudies-arrayexpress
TranscriptomicsTH-MYCN Mice with Caspase-8 Deficiency Develop Advanced Neuroblastoma with Bone Marrow Metastasis
Neuroblastoma, the most common extracranial pediatric solid tumor, is responsible for 15% of all childhood cancer deaths. Patients frequently present at diagnosis with metastatic disease, particularly to the bone marrow. Advances in therapy and understanding of the metastatic process have been lim...
ORGANISM(S): Mus musculus 
2013-05-22 | E-GEOD-42548 | biostudies-arrayexpress
UnknownPolymorphisms in nucleotide excision repair genes and endometrial cancer risk.
Not available
S-EPMC3169742 | biostudies-literature
UnknownPromoting Evidence-Based Practice in Acute Respiratory Distress Syndrome: A Systematic Review.
Not available
S-EPMC8078296 | biostudies-literature
UnknownA dual PI3 kinase/mTOR inhibitor reveals emergent efficacy in glioma.
Not available
S-EPMC2925230 | biostudies-literature
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