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TranscriptomicsTranscription profiling of human muscle biopises after standard diet and activity regimes
Muscle biopsies taken from vastus lateralis muscle of 15 men and 15 women after 3 days of standardized diet and activity to examine effects of sex and age; Subjects were either young adults (7 men and 7 women, 20-29 yr old) or older (8 men and 8 women, 65-75 yr old); Affymetrix U133A and U133B array...
ORGANISM(S): Homo sapiens 
2008-06-17 | E-GEOD-9676 | biostudies-arrayexpress
TranscriptomicsEffect of aryl hydrocarbon receptor (Ahr) gene knockout on expression profiles of murine hematopoietic stem cells
As part of a study of the role of the aryl hydrocarbon receptor (Ahr) in maintenance and senescence of hematopoietic stem cells (HSC), global gene expression profiling was done with HSC isolated from Ahr-knockout and wild-type mice. HSC from young-adult (8 wk old) AhR-KO mice had changes in express...
ORGANISM(S): Mus musculus 
2013-11-08 | E-GEOD-46976 | biostudies-arrayexpress
TranscriptomicsChanges in PBMC gene expression profiles after influenza vaccination in healthy human subjects
Daily sampling of peripheral blood from human subjects vaccinated for influenza was done immediately before vaccination and for 10 days after vaccination. Temporal patterns of gene expression, determined by RNA-seq, in unfractionated PBMC suggested migration of myeloid/dendritic cell lineage cells o...
ORGANISM(S): Homo sapiens 
2013-08-07 | E-GEOD-45735 | biostudies-arrayexpress
TranscriptomicsChanges in gene expression profiles of circulating B cells after influenza vaccination in healthy human subjects
Daily sampling of peripheral blood from human subjects vaccinated for influenza was done immediately before vaccination and for 10 days after vaccination. In B cells, 90% of transcriptomic variation in subjects who received influenza vaccine within the previous three years was explained by a single ...
ORGANISM(S): Homo sapiens 
2013-08-07 | E-GEOD-45734 | biostudies-arrayexpress
TranscriptomicsEffect of influenza vaccination on PBMC and B cell gene expression profiles in healthy humans
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2013-08-07 | E-GEOD-45764 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human MDA-MB-231 cells response to adenovirus expressed estradiol-ERalpha, estradiol-Erbeta, and ERE Binding defective mutants
This SuperSeries is composed of the following subset Series:; GSE9757: Response to estradiol-ERalpha; GSE9758: Response to estradiol-ERalpha ERE Binding defective mutant; GSE9759: Response to estradiol-Erbeta and estradiol-ERbeta ERE binding defective mutant Experiment Overall Design: Refer to indiv...
ORGANISM(S): Homo sapiens 
2008-06-16 | E-GEOD-9761 | biostudies-arrayexpress
TranscriptomicsEffect of wheel running exercise on gene expression in skeletal muscles of mice
This analysis was done to determine which muscle group has the most skeletal muscle transcriptional reponses to wheel running activity. Seven male mice with C57BL/6 genetic background were placed individually in cages with running wheels and allowed free access to the wheels 24 hr per day. Access to...
ORGANISM(S): Mus musculus 
2011-09-03 | E-GEOD-31843 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human cell response to estradiol-ERalpha
In addition to the estrogen responsive element (ERE)-dependent gene expression, E2-ERalpha regulates transcription through functional interactions with transfactors bound to their cognate regulatory elements on DNA, hence the ERE-independent signaling pathway. However, the relative importance of th...
ORGANISM(S): Homo sapiens 
2008-06-16 | E-GEOD-9757 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human cells transfected with the recombinant adenovirus bearing no cDNA (CMV) or cDNA for ERalpha 203/204/211E (3411E) for 48h
In addition to the estrogen responsive element (ERE)-dependent gene expression, E2-ERalpha regulates transcription through functional interactions with transfactors bound to their cognate regulatory elements on DNA, hence the ERE-independent signaling pathway. However, the relative importance of th...
ORGANISM(S): Homo sapiens 
2008-06-16 | E-GEOD-9758 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human ER negative cells response to estradiol-ERbeta and estradiol-ERbeta ERE binding defective mutant
In addition to the estrogen responsive element (ERE)-dependent gene expression, E2-ERbeta regulates transcription through functional interactions with transfactors bound to their cognate regulatory elements on DNA, hence the ERE-independent signaling pathway. However, the relative importance of the...
ORGANISM(S): Homo sapiens 
2008-06-16 | E-GEOD-9759 | biostudies-arrayexpress
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