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GenomicsMINCR is a MYC-induced lncRNA able to modulate MYC’s transcriptional network in Burkitt lymphoma cells
Despite the established role of the transcription factor MYC in cancer, little is known about the involvement of lncRNAs in mediating MYC’s function. Here we have intersected RNA-sequencing data from MYC-inducible cell lines, from a cohort of 91 mature B-cell lymphomas and from sorted germinal-cente...
EGAS00001001199 | EGA
TranscriptomicsGenome-wide DNA Methylation Analysis Reveals Novel Targets for Drug Development in Mantle Cell Lymphoma
Mantle Cell Lymphoma (MCL) is a mostly incurable malignancy arising from naïve B cells (NBC) in the mantle zone of lymph node follicles. We analyzed genome-wide methylation in MCL patients using the HELP (Hpa II tiny fragment Enrichment by Ligation mediated PCR) assay and found significant aberrancy...
ORGANISM(S): Homo sapiens 
2010-07-30 | E-GEOD-19243 | biostudies-arrayexpress
GenomicsGenome-wide identification of distinct miRNA-mRNA target regulation pairs in Non-Hodgkin lymphomas: a report from the ICGC MMML-Seq consortium
We obtained miRNA profiles by miRnome sequencing from ICGC MMML-Seq patients diagnosed with Burkitt lymphoma, diffuse large B-cell lymphoma and follicular lymphoma and provide evidence of subtype-specific miRNA expression differences. We describe differentially expressed, mutated, edited and not pre...
EGAS00001001394 | EGA
Genomicsena-DATASET-DKFZ-IBIOS-16-07-2015-15:45:02:488-51 - samples
Despite the established role of the transcription factor MYC in cancer, little is known about the impact of a new class of transcriptional regulators, the long non-coding RNAs (lncRNAs), on the way MYC is able to influence cellular transcriptome. To this aim we have intersected RNA-sequencing data f...
EGAD00001001441 | EGA
Genomicsena-DATASET-DKFZ-IBIOS-28-08-2015-09:49:06:632-229 - samples
RNA-sequencing data from teh hT-RPE-MycER cell line after MYC activation and after MINCR knock-down in conditions of MYC ON or OFF
EGAD00001001598 | EGA
GenomicsMMML associated cell line data
Data Access Committee EGAC00001000381
EGAC00001000381 | EGA
Genomicsena-DATASET-DKFZ-IBIOS-16-09-2015-13:05:30:578-414 - samples
After overexpression and knockdown of both described novel miRs nmiR-1 and nmiR-2 in BL cell lines (SU-DHL4 for nmiR-1 and Raji for nmiR-2), we performed regular RNA-Seq (including Mock controls for all cell lines) to identify their direct and indirect downstream mRNA targets.
EGAD00001001612 | EGA
Genomicsena-DATASET-DKFZ-IBIOS-06-10-2015-14:15:14:065-198 - samples
miRNA seq data of 13 cases (MMML)
EGAD00001001632 | EGA
Genomicsena-DATASET-DKFZ-IBIOS-23-09-2015-12:28:32:695-418 - samples
miRNA seq data of 43 cases out of dataset EGAD00001000650 (MMML)
EGAD00001001619 | EGA
Genomicsena-DATASET-DKFZ-IBIOS-17-08-2015-09:13:01:216-19 - samples
PAR-CLIP was performed on the Argonaute-2 protein (AGO2) in four lymphoma cell lines: Namalwa Raji SU-DHL-4 SU-DHL-6
EGAD00001001468 | EGA
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