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ProteomicsRNA polymerase II transcription with partially assembled TFIID complexes
RNA polymerase II (Pol II) transcription initiation starts with the assembly of the preinitiation complex (PIC) on core promoters. The PIC is composed of six general transcription factors (GTFs). The recognition of the core promoter sequences by the TFIID GTF complex is the first step of the PIC ass...
ORGANISM(S): Mus musculus (Mouse) 
2024-05-21 | PXD046459 | Pride
Transcription Rna polymerase Tfiid 
UnknownAnalysis of biogeographic ancestry reveals complex genetic histories for indigenous communities of St. Vincent and Trinidad.
Not available
S-EPMC8095721 | biostudies-literature
UnknownA Multiple Protease Strategy to Optimise the Shotgun Proteomics of Mature Medicinal Cannabis Buds.
Not available
S-EPMC6888629 | biostudies-literature
ProteomicsMilk bottom-up proteomics: method optimisation.
Milk is a complex fluid whose proteome displays a diverse set of proteins of high abundance such as caseins and medium to low abundance whey proteins such as ß-lactoglobulin, lactoferrin, immunoglobulins, glycoproteins, peptide hormones and enzymes. A sample preparation method that enables high repr...
ORGANISM(S): Bos taurus (Bovine) 
2016-01-26 | PXD002529 | Pride
Replicates. Jersey and holstein cow milk Trypsin digestion Proteome Nlc-esi-ms 
ProteomicsProteomic analyses of V. cholerae phage ICP1 and the phage satellite PLE11
ICP1 is a predominant lytic phage of the Vibrio cholerae, the causative pathogen of diarrheal disease of cholera. A mobile genetic element called PLE (Phage inducible chromosomal island-like element) is often integrated into the V. cholerae chromosome, which is activated to excise only upon ICP1. PL...
ORGANISM(S): Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) Vibrio phage ICP1_2006_E 
2026-01-08 | PXD058665 | Pride
UnknownClinical characteristics and outcomes of patients with Corona Virus Disease 2019 (COVID-19) at Mercy Health Hospitals, Toledo, Ohio.
Not available
S-EPMC8061926 | biostudies-literature
MetabolomicsSmall Polar Hits against S. aureus: Screening, Initial Hit Optimization, and Metabolomic Studies
The global prevalence of antibacterial resistance requires new antibacterial drugs with novel chemical scaffolds and modes of action. It is also vital to design compounds with optimal physicochemical properties to permeate the bacterial cell envelope. We described an approach of combining and integr...
2021-11-04 | MTBLS788 | MetaboLights
UnknownCharacterization of an unusual Mycobacterium: a possible missing link between Mycobacterium marinum and Mycobacterium ulcerans.
Not available
S-EPMC120612 | biostudies-literature
UnknownRandomized phase II trial of erlotinib alone or with carboplatin and paclitaxel in patients who were never or light former smokers with advanced lung adenocarcinoma: CALGB 30406 trial.
Not available
S-EPMC3397694 | biostudies-literature
MetabolomicsInhibition of glycolysis and mitochondrial respiration promotes radiosensitisation of neuroblastoma and glioma cells

BACKGROUND: Neuroblastoma accounts for 7% of paediatric malignancies but is responsible for 15% of all childhood cancer deaths. Despite rigorous treatment involving chemotherapy, surgery, radiotherapy and immunotherapy, the 5-year overall survival rate of high-risk disease remai...

2022-11-30 | MTBLS858 | MetaboLights
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