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UnknownWRN mutations in Werner syndrome patients: genomic rearrangements, unusual intronic mutations and ethnic-specific alterations.
Not available
S-EPMC4686336 | biostudies-literature
MetabolomicsPhospholipid acyl chain diversity controls the tissue-specific assembly of mitochondrial cardiolipins

Cardiolipin (CL) is a phospholipid specific for mitochondrial membranes and crucial for many core tasks of this organelle. Its side chain configurations are tissue-specific, functionally important and generated via post-biosynthetic remodeling. However, this process lacks the necessary specificit...

2020-05-22 | MTBLS1446 | MetaboLights
TranscriptomicsTranscriptional profiling by array in rat of age-dependent gene expression in sensorimotor cortex following spinal cord injury
In this study, we investigated the extent and nature of the difference between the dynamic cortical gene expression profiles of aged (22-month-old) and young (2-month-old) rats following thoracic corticospinal tract (CST) transection and whether the anti-scarring-treatment (AST)-induced regeneration...
ORGANISM(S): Rattus norvegicus 
2012-01-15 | E-MTAB-794 | biostudies-arrayexpress
TranscriptomicsDifferent exercise modalities have distinct effects on the transcriptome profile in the male rat femoral diaphysis
Mechanical loading is a key determinant of bone mass, geometry and strength and is essential to maintain optimal skeletal health. We hypothesized that spontaneous low-impact exercise would affect global gene transcript levels in cortical bone of growing rats. We used RNA-Seq to analyse the transcrip...
ORGANISM(S): Rattus norvegicus 
2015-11-02 | E-GEOD-67787 | biostudies-arrayexpress
TranscriptomicsTranscriptomic alterations induced by AT-EAE in mouse spinal cord
We compared RNA samples extracted from spinal cords of control (C) and AT-EAE (E) mice using the "Multiple Yellow" strategy. 4 distinct C-extracts were hybridized with two slides and 4 distinct E-extracts with other two slides, and the green/red normalized signals were compared separately and the E/...
ORGANISM(S): Mus musculus 
2010-06-10 | E-GEOD-2446 | biostudies-arrayexpress
ProteomicsProfiling of Kallikrein Proteases and Global Proteome Biology of PDAC, Chronic Pancreatitis and Normal Pancreas
Cell conditioned medium from human pancreatic cancer cell lines MiaPaCa-2, AsPC-1, primary pancreatic cell lines as well as human FFPE tissue samples from pancreatic ductal adenocarcinoma (PDAC), chronic pancreatitis (CP), ampullary cancer, non-malignant adjacent pancreas and normal pancreas were an...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000090255 | MassIVE
TranscriptomicsMicroRNA array analysis during the regenerative peak following rat liver resection
The liver has the unique capacity to regenerate after surgical resection. However, the regulation of liver regeneration is not completely understood. We performed miRNA microarray analyses of liver tissue from Wistar rats at different time points after 70% partial hepatectomy (0, 2, 6, 12, 24, 48 ho...
ORGANISM(S): Rattus norvegicus 
2011-03-28 | E-GEOD-23696 | biostudies-arrayexpress
UnknownMechanism of BRCA1-BARD1 function in DNA end resection and DNA protection.
Not available
S-EPMC11464378 | biostudies-literature
UnknownCell-free DNA in plasma and ascites as a biomarker of bevacizumab response- a translational research sub-study of the REZOLVE (ANZGOG-1101) clinical trial.
Not available
S-EPMC10966381 | biostudies-literature
ProteomicsProteomics of Small Extracellular Vesicles from Melanoma DCC-Derived Cell Lines
Small extracellular vesicles (sEVs) were isolated from the culture supernatant of melanoma DCC-derived cell lines (MelDCC) after 48 hours of serum-free culture. sEVs were obtained through differential ultracentrifugation, specifically as the 100K pellet, following the protocol described in detail by...
ORGANISM(S): Homo sapiens (Human) 
2025-02-24 | PXD059510 | Pride
Lc-ms/ms Melanoma Extracellular vesicles 
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