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TranscriptomicsIdentification of genes critical for resistance to infection by West Nile virus using RNA-Seq analysis
Background: West Nile virus is an emerging infection of biodefense concern and there are no available treatments or vaccines. Here we used a high-throughput method based on a novel gene expression analysis, RNA-Seq, to give a global picture of differential gene expression by primary human macrophage...
ORGANISM(S): Homo sapiens 
2014-01-08 | E-GEOD-40718 | biostudies-arrayexpress
TranscriptomicsTranscription profile of K-ras activated murine menstruating uteri
The expression of K-ras transgene is induced in K-rasV12+/-/Cre+/+/ROSA26R-LacZ+/+ transgenic mice uteri, which were primed with hormone treatment. Decidualization was artificially induced in these uteri and hormone injection was withdrawn to induced menstruation-like endometrial degeneration. Micr...
ORGANISM(S): Mus musculus 
2010-06-20 | E-GEOD-15518 | biostudies-arrayexpress
TranscriptomicsTranscriptional profile of mice with good and poor spatial learning during West Nile virus recovery
Greater than 50% of patients who survive neuroinvasive West Nile virus (WNV), a mosquito-borne, positive-sense strand flavivirus, exhibit cognitive sequelae including memory impairments which may last several years. High survival rates from WNV neuroinvasive disease (WNND) (>90%) have led to hundred...
ORGANISM(S): Mus musculus 
2016-06-27 | E-GEOD-72139 | biostudies-arrayexpress
TranscriptomicsGene expression analysis of a deltamethrin resistant populations of Anopheles coluzzi from south-west Burkina Faso in 2012.
Transcriptome profiling of Anopheles coluzzi mosquitoes collected from two sites in south west Burkina Faso (Vallee du Kou & Tengrela) displaying a deltamethrin resistant phenotype. The resistant insects were compared to two laboratory insecticide susceptible strains.
ORGANISM(S): Anopheles gambiae 
2014-12-31 | E-MTAB-2859 | biostudies-arrayexpress
TranscriptomicsGene expression profiles of spontaneous metastasis in a K-ras/p53 mutant mouse model
The biologic basis for NSCLC metastasis is not well understood. Here we addressed this deficiency by transcriptionally profiling tumors from a genetic mouse model of human lung adenocarcinoma that develops metastatic disease owing to the expression of K-rasG12D and p53R172H. We identified 2,209 gene...
ORGANISM(S): Mus musculus 
2009-04-14 | E-GEOD-14449 | biostudies-arrayexpress
UnknownEfficacy and safety of KL-A167 in previously treated recurrent or metastatic nasopharyngeal carcinoma: a multicenter, single-arm, phase 2 study.
Not available
S-EPMC9985015 | biostudies-literature
UnknownKPC enzymes in the UK: an analysis of the first 160 cases outside the North-West region.
Not available
S-EPMC4830413 | biostudies-literature
TranscriptomicsAnalysis of Culex quinquefasciatus responses to WNV infection
Analysis of Culex quinquefasciatus responses to West Nile virus (WNV) infection at 7 and 14 days after ingestion of infected blood in the gut and carcass tissues. Comparison of WNV-infected to non-infected carcass and gut samples.
ORGANISM(S): Culex quinquefasciatus 
2011-11-01 | E-GEOD-23045 | biostudies-arrayexpress
UnknownIdentification of the vitamin K-dependent carboxylase active site: Cys-99 and Cys-450 are required for both epoxidation and carboxylation.
Not available
S-EPMC27173 | biostudies-literature
UnknownWest Nile virus from blood donors, vertebrates, and mosquitoes, Puerto Rico, 2007.
Not available
S-EPMC2815984 | biostudies-literature
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