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UnknownAsymmetric catalytic N-phosphonyl imine chemistry: the use of primary free amino acids and Et2AlCN for asymmetric catalytic Strecker reaction.
Not available
S-EPMC2912979 | biostudies-literature
ProteomicsBenchmarking blood collection tubes and processing intervals for extracellular vesicle performance metrics
Extracellular vesicle (EV) analysis from blood samples is under intense investigation and holds the potential to deliver clinically meaningful biomarkers for health and disease. Technical variation must be minimized to confidently assess EV-associated biomarkers but the impact of pre-analytics on EV...
ORGANISM(S): Homo sapiens (Human) 
2023-03-13 | PXD035199 | Pride
Biomarkers  proteomics  extracellular vesicles  exosomes  serum  plasma  anticoagulants  preservatives  cancer 
TranscriptomicsStereo-seq analysis of human multiple sclerosis white matter lesions
Fresh frozen samples from human white matter MS lesions. Using Stereo-seq we compared mixed active/inactive lesions with lipid-laden foamy microglia with lesions containing ramified microglia. Study includes post-mortem subcortical white matter (WM) tissue of n = 7 donors with MS (5 females, 2 male...
ORGANISM(S): Homo sapiens 
2026-05-11 | E-MTAB-17040 | biostudies-arrayexpress
TranscriptomicsHuman MCF-7 breast cancer cells: control vs. treated with conditioned medium of cancer associated adipose tissue
Transcriptional profiling of human MCF-7 breast cancer cells comparing MCF-7 cells treated with control medium (DMEM/F12 + 0,5% BSA) with MCF-7 cells treated with conditioned medium of cancer-associated adipose tissue (CMCAAT) obtained from 2 breast cancer patients. Goal was to determine the effects...
ORGANISM(S): Homo sapiens 
2015-01-07 | E-GEOD-58574 | biostudies-arrayexpress
ProteomicsUnravelling the proteomic landscape of extracellular vesicles in prostate cancer by density-based fractionation of urine
Mass spectrometry-based proteomic analysis of urinary EV (uEV) in men with benign and malignant prostate disease, profiling the proteome of EV separated from prostate tumor interstitial fluid and matched uEV, and a comparative proteomic analysis with uEV from patients with bladder and renal cancer.
ORGANISM(S): Homo sapiens (Human) 
2020-04-09 | PXD015289 | Pride
Extracellular vesicles  exosomes  separation  isolation  urine  cancer  biomarkers 
TranscriptomicsToxicogenomic response of Rhodospirillum rubrum S1H to the model micropollutant triclosan
Aiming at the development of a micropollutant biosensor in the frame of the Micro-Ecological Life Support System Alternative (MELiSSA), a pilot study was initiated to identify triclosan (TCS)-responsive biomarker genes in the MELiSSA carbon-mineralizing microorganism, Rhodospirillum rubrum S1H. TCS ...
ORGANISM(S): Rhodospirillum rubrum 
2010-05-19 | E-GEOD-16189 | biostudies-arrayexpress
UnknownWater-Soluble Anthraquinone Photocatalysts Enable Methanol-Driven Enzymatic Halogenation and Hydroxylation Reactions.
Not available
S-EPMC7418218 | biostudies-literature
UnknownCardiac Rotational Mechanics As a Predictor of Myocardial Recovery in Heart Failure Patients Undergoing Chronic Mechanical Circulatory Support: A Pilot Study.
Not available
S-EPMC5901885 | biostudies-literature
ProteomicsA preclinical platform for assessing long-term drug efficacy exploiting mechanically tunable scaffolds colonized by a three-dimensional tumor microenvironment
Background: Long-term drug evaluation heavily relies upon rodent models. Drug discovery methods to reduce animal models in oncology may include three-dimensional (3D) cellular systems that take into account tumor microenvironment (TME) cell types and biomechanical properties. Methods: In this study...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD039590 | Pride
3d cancer model  long-term  drug evaluation  pre-clinical  micro-environment  stiffness 
UnknownConvergent Synthesis of Sialyl LewisX- O-Core-1 Threonine.
Not available
S-EPMC7648531 | biostudies-literature
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