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TranscriptomicsExpression data from proximal jejunum of WT vs. TLR2 KO mice after methotrexate (MTX) treatment
The role of innate immunity in modulating severity of chemotherapy-induced complications is so far unclear. The aim of this study was to determine how TLR2 may influence MTX-induced mucositis in the small intestine in mice. We used microarrays to assess gene expression profiles in proximal jejunum o...
ORGANISM(S): Mus musculus 
2015-01-24 | E-GEOD-56426 | biostudies-arrayexpress
TranscriptomicsTranscriptomic responses of Anguilla anguilla elvers fed dietary LPS
Dietary immunostimulants are considered as an effective tool for enhancing the immune status of cultured organisms and improving their general welfare. Immunostimulants are chemical substances which activate transiently elements of the immune response and may potentially render animals more resistan...
ORGANISM(S): Anguilla anguilla 
2016-07-31 | E-GEOD-53346 | biostudies-arrayexpress
GenomicsChIP-seq of MYST acetyltransferases
Histone acetyltransferases (HAT) assemble into multisubunit complexes in order to target distinct lysine residues on nucleosomal histones. Here, we characterize native HAT complexes assembled by the BRPF-family of scaffold proteins. Their PHD-ZnKnuckle-PHD domain is essential for binding chromatin...
ORGANISM(S): Homo sapiens 
2013-10-09 | E-GEOD-47190 | biostudies-arrayexpress
UnknownCOVID-19 due to the B.1.617.2 (Delta) variant compared to B.1.1.7 (Alpha) variant of SARS-CoV-2: a prospective observational cohort study.
Not available
S-EPMC9240087 | biostudies-literature
GenomicsIntegrative analysis of the zinc finger transcription factor Lame duck in the Drosophila myogenic gene regulatory network
Contemporary high throughput technologies permit the rapid identification of transcription factor (TF) target genes on a genome-wide scale, yet the functional significance of TFs requires knowledge of target gene expression patterns, cooperating TFs and cis-regulatory element (CRE) structures. Here...
ORGANISM(S): Drosophila melanogaster 
2012-11-13 | E-GEOD-38402 | biostudies-arrayexpress
UnknownLoci for insulin processing and secretion provide insight into type 2 diabetes risk.
Not available
S-EPMC9943750 | biostudies-literature
GenomicsExpanding the Catalog of Enhancer Marks In Vivo
While the majority of protein-coding genes in the human genome have been identified, the location of the regulatory sequences that control their expression in time and space remains poorly defined. The importance of identifying these elements is underscored by a growing number of studies (such as GW...
ORGANISM(S): Mus musculus 
2014-04-16 | E-GEOD-37151 | biostudies-arrayexpress
UnknownFine-mapping classical HLA variation associated with durable host control of HIV-1 infection in African Americans.
Not available
S-EPMC3441117 | biostudies-literature
UnknownIntrapartum Sildenafil to Improve Perinatal Outcomes: A Randomized Clinical Trial.
Not available
S-EPMC12150225 | biostudies-literature
UnknownVariants in MTNR1B influence fasting glucose levels.
Not available
S-EPMC2682768 | biostudies-literature
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