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Proteomics,MultiomicsSystematic Discovery of TLR Signaling Components Delineates Viral-Sensing Circuits.
Chevrier N, Mertins P, Artyomov MN, Shalek AK, Iannacone M, Ciaccio MF, Gat-Viks I, Tonti E, DeGrace MM, Clauser KR, Garber M, Eisenhaure TM, Yosef N, Robinson J, Sutton A, Andersen MS, Root DE, von Andrian U, Jones RB, Park H; Carr SA, Regev A, Amit I, Hacohen N. Cell, 2011, 147(4) 853-867. doi: 10...
2013-12-10 | MSV000078507 | MassIVE
TranscriptomicsConserved molecular interactions within MYST-ING acetyltransferase complexes that regulate cell proliferation
This SuperSeries is composed of the following subset Series: GSE33007: Genome-wide map of HBO1 in cancer derived human cell line GSE33220: Effects of the JADE-HBO1 complex on gene expression Refer to individual Series
ORGANISM(S): Homo sapiens 
2012-03-15 | E-GEOD-33221 | biostudies-arrayexpress
TranscriptomicsIkaros mutation confers integrin-dependent pre-B cell survival and progression to acute lymphoblastic leukemia
Deletion of the Ikaros DNA-binding domain generates dominant-negative isoforms that interfere with Ikaros family activity and correlate with poor prognosis in human precursor B cell acute lymphoblastic leukemias (B-ALL).  Here, we show that conditional inactivation of the Ikaros DNA binding domain i...
ORGANISM(S): Mus musculus 
2014-02-09 | E-GEOD-53401 | biostudies-arrayexpress
TranscriptomicsWhole-Genome Gene Expression Bead Array analysis of Toll-like receptor 2/8 stimulated human monocytes
Monocytes and macrophages are essential cells in the early response in their capacity as ubiquitous phagocytic cells. They phagocytose microorganisms or damaged cells and sense pathogen/damage-associated molecular patterns (PAMPs/DAMPs) through innate receptors such as Toll-like receptors (TLRs). We...
ORGANISM(S): Homo sapiens 
2018-03-09 | E-MTAB-6222 | biostudies-arrayexpress
UnknownCell envelope growth of Gram-negative bacteria proceeds independently of cell wall synthesis
Not available
S-SCDT-10_15252-EMBJ_2022112168 | biostudies-other
UnknownDe novo truncating variants in the AHDC1 gene encoding the AT-hook DNA-binding motif-containing protein 1 are associated with intellectual disability and developmental delay.
Not available
S-EPMC4850891 | biostudies-literature
TranscriptomicsTranscription profiling of primary human astrocytes from brain treated by stathmin, poly IC and ultrapure LPS to examine the effects of different Toll-like receptor agonists
Goal of the experiment was to examine the effects of different Toll-like receptor agonists on the human astrocyte response, in termsof levels of transcripts encoding cytokines, chemokines and theirreceptors. Stathmin and poly IC are considered as agonist for TLR3, LPSas an agonist for TLR4. The manu...
ORGANISM(S): Homo sapiens 
2010-02-11 | E-TABM-851 | biostudies-arrayexpress
UnknownAn assessment of the role of vinculin loss of function variants in inherited cardiomyopathy.
Not available
S-EPMC7714388 | biostudies-literature
ProteomicsTranscriptomic and proteomic insights into innate immunity and adaptations to a symbiotic lifestyle in the gutless marine worm Olavius algarvensis
Transcriptomic and proteomic insights into innate immunity and adaptations to a symbiotic lifestyle in the gutless marine worm Olavius algarvensis
ORGANISM(S): Olavius Algarvensis (ncbitaxon:188229) 
2016-02-12 | MSV000079512 | MassIVE
TranscriptomicsRNA-seq from heart tissue of 192 heterogeneous stock rats
We measured heart gene expression in 192 heterogeneous stock rats. These animals were part of a larger cohort that were extensively phenotyped and genotyped and originally published in PMID: 23708188, although the gene expression data here were not included in that study.
ORGANISM(S): Rattus norvegicus 
2023-04-03 | E-MTAB-12701 | biostudies-arrayexpress
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