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MetabolomicsLongitudinal multi-omics reveals subset-specific mechanisms underlying irritable bowel syndrome

The gut microbiome has been implicated in multiple human chronic gastrointestinal (GI) disorders. Determining its mechanistic role in disease has been difficult due to apparent disconnects between animal and human studies and lack of an integrated multi-omics view of disease-specific physiologica...

2020-09-08 | MTBLS1396 | MetaboLights
TranscriptomicsFGF-dependent regulation of VEGF signaling via transcriptional control of VEGF receptor 2 expression
Numerous studies have suggested a link between fibroblast growth factor (FGF) and vascular endothelial growth factor (VEGF) signaling pathways; however the nature of this link has not been established. To evaluate this relationship we investigated VEGF signaling in endothelial cells with disrupted F...
ORGANISM(S): Mus musculus 
2011-06-07 | E-GEOD-28483 | biostudies-arrayexpress
UnknownMicrobial community composition explains soil respiration responses to changing carbon inputs along an Andes-to-Amazon elevation gradient.
Not available
S-EPMC4263258 | biostudies-literature
TranscriptomicsCalorie/Dietary Restriction and Resveratrol in Female Drosophila Melanogaster Head/Thorax
Feeding resveratrol to Drosophila melanogaster extends lifespan. Studies of microarray show similarities between calorie/dietary restriction and resveratrol on both a gene expression and biological pathway level. 9 samples: 3 biological replicates each of normal diet, restricted diet and normal diet...
ORGANISM(S): Drosophila melanogaster 
2011-07-20 | E-GEOD-26724 | biostudies-arrayexpress
UnknownInfluence of doctor-patient conversations on behaviours of patients presenting to primary care with new or persistent symptoms: a video observation study.
Not available
S-EPMC7057803 | biostudies-literature
TranscriptomicsTranscription profiling of mouse WT and Cav-3 knockouts on FVB/N genetic background mammary glands reveals loss of caveolin-3 induces the development of a lactogenic microenvironment
Here, we show that functional loss of a single gene is sufficient to confer constitutive milk protein production and protection against mammary tumor formation. Caveolin-3 (Cav-3), a muscle-specific caveolin-related gene, is highly expressed in striated and smooth muscle cells. We demonstrate that C...
ORGANISM(S): Mus musculus 
2009-01-31 | E-GEOD-12881 | biostudies-arrayexpress
UnknownExcellent outcome of young children with nodular desmoplastic medulloblastoma treated on "Head Start" III: a multi-institutional, prospective clinical trial.
Not available
S-EPMC7746930 | biostudies-literature
UnknownInfant HIV type 1 gp120 vaccination elicits robust and durable anti-V1V2 immunoglobulin G responses and only rare envelope-specific immunoglobulin A responses.
Not available
S-EPMC4318918 | biostudies-literature
GenomicsEGAS00001000262-sc-2023-03-27T08:52:54Z - samples
This dataset includes Illumina EPIC Capture Sequencing Data of 376 samples from 188 men with prostate cancer. Samples were taken from primary tissue obtained at prostatectomy, with matched pathologically assessed non-cancer control material. This DNA methylation data includes donors and samples incl...
EGAD00001010184 | EGA
Genomicsena-DATASET-SC-16-09-2014-14:22:12:125-153 - samples
Description not provided
EGAD00001001014 | EGA
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