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MetabolomicsNitrate-Sialin2 Axis Couples ER-Mitochondrial Calcium Signaling with Fatty Acid Metabolism to Drive White Adipose Browning
Nutrient cues shape adipose homeostasis; however, the mechanism by which inorganic signals engage organelle networks to drive white fat browning remains unclear. Here, we identify a nitrate-Sialin2 pathway that converts dietary nitrate into a spatially confined thermogenic program. Sialin2 localizes...
2026-05-17 | MTBLS14192 | MetaboLights
TranscriptomicsWhite Matter transcriptome in chronic alcoholism
Chronic alcohol consumption can lead to alchohol-related brain damage (ARBD). Despite the well known acute effects of alcohol the mechanism responsible for chronic brain damage is largely unknown. Pathologically the major change is the loss of white matter while neuronal loss is mild and restricted ...
ORGANISM(S): Homo sapiens 
2014-01-04 | E-GEOD-53808 | biostudies-arrayexpress
TranscriptomicsGenome wide methylation array analysis in T-ALL
In short: Genome wide promoter DNA methylation profiling of 43 T-ALL samples and 5 T-cell controls (normal bone marrow and stimulated T-cells) . The Illumina Infinium 27k Human DNA methylation Beadchip v1.2 was used to obtain DNA methylation profiles across approximately 27,000 CpGs. Manuscript abst...
ORGANISM(S): Homo sapiens 
2013-07-01 | E-GEOD-42079 | biostudies-arrayexpress
UnknownHSD17B7 gene in self-renewal and oncogenicity of keratinocytes from Black versus White populations.
Not available
S-EPMC8261506 | biostudies-literature
MetabolomicsBased on the Metabolomic Approach the Energy Metabolism Responses of Oriental River Prawn Macrobrachium nipponense Hepatopancreas to Acute Hypoxia and Reoxygenation
Hypoxia represents a major physiological challenge for prawns and is a problem in aquaculture. Therefore, an understanding of the metabolic response mechanism of economically important prawn species to hypoxia and re-oxygenation is essential. However, little is known about the intrinsic mechanisms b...
2021-05-17 | MTBLS584 | MetaboLights
TranscriptomicsHL_Arabidopsis_gpa1-4
Arabidopsis thaliana plants from the genotypes Col-0 and gpa1-4 (knock-out) were used. They were grown in a growth chamber for 5 weeks in short day (8/16 light/dark cycle at 22 degrees, 150 umol*m2*s-1 (fluorescent lights) and 55% RH in 100-ml pots with Levingtons L2+S. On the day of the experiment,...
ORGANISM(S): Arabidopsis thaliana 
2014-02-10 | E-MTAB-2050 | biostudies-arrayexpress
UnknownLesion-remote astrocytes govern microglia-mediated white matter repair.
Not available
S-EPMC12823418 | biostudies-literature
UnknownCombined impact of gray and superficial white matter abnormalities: Implications for epilepsy surgery.
Not available
S-EPMC12605822 | biostudies-literature
TranscriptomicsTranscription profiling of liver and small intestine from Cyp3a/Mdr1a/1b knock-out mice and wild-type mice
comparison Cyp3a/Mdr1a/1b ko mice with wild-type mice (both FVB background)
ORGANISM(S): Mus musculus 
2009-07-01 | E-NCMF-26 | biostudies-arrayexpress
UnknownChronic kidney disease, cerebral blood flow, and white matter volume in hypertensive adults.
Not available
S-EPMC4818564 | biostudies-literature
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