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Transcriptomicsc-Myc binding in HL60 cells
Analysis of technical variance of ChIP-on-Chip studies by characterization of Myc-binding in HL60 cells. Keywords: Chip-on-chip Characterization of c-Myc binding in HL60 cells. Thirteen biologically independent replicates of growing HL60 cells were subjected to ChIP with an N-terminal c-Myc antibod...
ORGANISM(S): Homo sapiens 
2010-05-17 | E-GEOD-8447 | biostudies-arrayexpress
TranscriptomicsRacial Difference in Human Platelet PAR4 Reactivity Reflects Expression of PCTP and miR-376c
Racial differences in the pathophysiology of atherothrombosis are poorly understood. We explored the function and transcriptome of platelets in healthy black (n=70) and white (n=84) subjects. Numerous differentially expressed (DE) RNAs were associated with both race and PAR4 reactivity, including p...
ORGANISM(S): Homo sapiens 
2013-11-15 | E-GEOD-49921 | biostudies-arrayexpress
TranscriptomicscirDNA methylome analysis in prostate cancer
DNA modification profiling of circulating DNA (cirDNA) from plasma samples from prostate cancer patients (T2-3N0Mx), benign prostatic hyperplasia and control individuals Epigenetic differences are a common feature of many diseases, including cancer, and disease-associated changes have even been dete...
ORGANISM(S): Homo sapiens 
2012-07-09 | E-GEOD-36195 | biostudies-arrayexpress
TranscriptomicsmiRNA chronic OVA aerosol
specific pathogen-free female BALB/c mice aged 7-8 weeks (Animal Resources Centre, Perth, Western Australia) were systemically sensitised by intraperitoneal injection of 50 M-5g of alum-precipitated chicken egg OVA (Grade V, ?98% pure, Sigma Australia) 21 and 7 days before inhalational challenge, th...
ORGANISM(S): Mus musculus 
2011-06-10 | E-MEXP-3118 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Salmonella enterica (I) serovar Typhi Ty2 wild type and ompR null strains in a strand-specific manner
Analysis of transcriptome in a strand-specific manner to further refine previous genome annotation; RNA-seq was also combined with microarray and proteome analysis to further define the S. Typhi ompR regulon and identify novel ompR regulated transcripts.
ORGANISM(S): Salmonella enterica 
2009-03-03 | E-TABM-644 | biostudies-arrayexpress
no omics definedA coordintate global control over cellular transcription
Although much is known about the regulation of eukaryotic transcription, the global controls which determine rates of total transcription within a cell are not well understood. We have investigated the effects that the DNA to protein ratio has on both total cellular transcription and the transcripti...
ORGANISM(S): Schizosaccharomyces pombe 
2011-09-23 | E-TABM-1075 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of grapevine cell culture treated with methyly jasmonate, salicylic acids and ethanol controls
Calli generated from grape berries were used to establish a cell suspension in Gamborgs B5 liquid medium with minimal organics supplemented with 30 gL-1 sucrose, 0.25 gL-1 casein hydrolysate, 0.93 ?M kinetin and 0.54 ?M naphthaleneacetic acid (NAA) and incubated in darkness at 26°C.
The cells w...
ORGANISM(S): Vitis vinifera 
2009-04-28 | E-MEXP-1524 | biostudies-arrayexpress
TranscriptomicsCharacterization of technical variation in ChIP-on-chip studies
Analysis of technical variance of ChIP-on-Chip studies by characterization of Myc-binding in HL60 cells. Keywords: Chip-on-chip Fully-blocked study of technical variance in Myc-binding in HL60 cells. Two different antibodies were used to generate 6 biologically independent replicates each. Each repl...
ORGANISM(S): Homo sapiens 
2008-10-31 | E-GEOD-8448 | biostudies-arrayexpress
TranscriptomicssnRNA-seq of cortices from a MCT8-OATP1C1-deficient Allan-Herndon-Dudley Syndrome mouse model
Allan-Herndon-Dudley syndrome (AHDS) is a rare disorder caused by faulty thyroid hormone transport to the brain, leading to severe movement problems and intellectual disability. Our study in a murine model of the AHDS used snRNAseq to gain deep insights into individual cortical cells, aiming to unra...
ORGANISM(S): Mus musculus 
2026-08-07 | E-MTAB-16567 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human primary B-cell vs monocyte-derived dendritic cells
Genome-wide RNAi screen reveals new pathways for MHC class II antigen presentation
ORGANISM(S): Homo sapiens 
2010-12-18 | E-MTAB-192 | biostudies-arrayexpress
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