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MetabolomicsIncreased fatty acid metabolism and decreased glycolysis are hallmarks of metabolic reprogramming within microglia in degenerating white matter during recovery from experimental stroke
The goal of this study was to evaluate changes in metabolic homeostasis during the first 12 weeks of recovery in a distal middle cerebral artery occlusion mouse model of stroke. To achieve this goal, we compared the brain metabolomes of ipsilateral and contralateral hemispheres from aged male mice u...
2022-10-06 | MTBLS5543 | MetaboLights
TranscriptomicsGene expression microarray of human pulmonary endothelial cells from patients with Chronic Obstructive Pulmonary Disease in comparison with normal controls
This experiment was carried out to see if there were any gene expression differences in pulmonary endothelial cells between patients with and without COPD. COPD is an inflammatory condition and although much work has previously been performed to investigate the inflammatory cells in COPD there has n...
ORGANISM(S): Homo sapiens 
2019-02-28 | E-MTAB-7671 | biostudies-arrayexpress
TranscriptomicsGene expression microarray of human pulmonary endothelial cells from patients with Chronic Obstructive Pulmonary Disease in comparison with normal controls.
This experiment was carried out to see if there were any gene expression differences in pulmonary endothelial cells between patients with and without COPD. COPD is an inflammatory condition and although much work has previously been performed to investigate the inflammatory cells in COPD there has n...
ORGANISM(S): Homo sapiens 
2018-09-18 | E-MTAB-7140 | biostudies-arrayexpress
TranscriptomicsGene Expression Profiles in a Rabbit Model of Systemic Lupus Erythematosus
We previously reported the establishment of a rabbit (Oryctolagus cuniculus) model of Systemic Lupus Erythematosus (SLE) in which peptide immunization led to lupus-like autoantibody production including anti-Sm, -RNP, -SS-A, -SS-B and -dsDNA. Some neurological symptoms in form of seizures and nystag...
ORGANISM(S): Oryctolagus cuniculus 
2010-07-23 | E-GEOD-23076 | biostudies-arrayexpress
TranscriptomicsmiRNA microarray of human pulmonary endothelial cells comparing patients with and without Chronic Obstructive Pulmonary Disease.
This experiment was carried out to see if there were any miRNA expression differences in pulmonary endothelial cells between patients with and without COPD. COPD is an inflammatory condition and although much work has previously been performed to investigate the inflammatory cells in COPD there has ...
ORGANISM(S): Homo sapiens 
2018-09-10 | E-MTAB-7141 | biostudies-arrayexpress
TranscriptomicsPulmonary microRNA changes alter angiogenesis in chronic obstructive pulmonary disease and lung cancer
This experiment was carried out to see if there were any miRNA expression differences in pulmonary endothelial cells between patients with and without COPD. COPD is an inflammatory condition and although much work has previously been performed to investigate the inflammatory cells in COPD there has ...
ORGANISM(S): Homo sapiens 
2021-08-01 | E-MTAB-10311 | biostudies-arrayexpress
ProteomicsStandardization of mitochondrial proteomics v2 NP
Comparison of the extraction performances of three different mitochondria enrichment protocols (differential centrifugation, sucrose gradient, a commercial kit based on surfactants) on ten different cell lines. Samples were analysed on several instrumental platforms. Mitochondrial pellets were lysed...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-07-14 | MSV000081329 | MassIVE
TranscriptomicsTranscription profiling of human and mouse ependymomas: Comparative genomics matches mutations and cells to generate faithful ependymoma models
Genomic technologies have unmasked molecularly distinct subgroups among tumors of the same histological type; but understanding the biologic basis of these subgroups has proved difficult since their defining alterations are often numerous, and the cellular origins of most cancers remain unknown. We...
ORGANISM(S): Homo sapiens 
2010-07-19 | E-GEOD-21687 | biostudies-arrayexpress
ProteomicsStandardization of mitochondrial proteomics
Comparison of the extraction performances of three different mitochondria enrichment protocols (differential centrifugation, sucrose gradient, a commercial kit based on surfactants) on ten different cell lines. Samples were analysed on several instrumental platforms. Mitochondrial pellets were lysed...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-05-30 | MSV000081121 | MassIVE
UnknownPathophysiology of multiple sclerosis damage and repair: Linking cerebral hypoperfusion to the development of irreversible tissue loss in multiple sclerosis using magnetic resonance imaging.
Not available
S-EPMC7615142 | biostudies-literature
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