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MetabolomicsIncreased fatty acid metabolism and decreased glycolysis are hallmarks of metabolic reprogramming within microglia in degenerating white matter during recovery from experimental stroke
The goal of this study was to evaluate changes in metabolic homeostasis during the first 12 weeks of recovery in a distal middle cerebral artery occlusion mouse model of stroke. To achieve this goal, we compared the brain metabolomes of ipsilateral and contralateral hemispheres from aged male mice u...
2022-10-06 | MTBLS5543 | MetaboLights
TranscriptomicsTranscriptome analysis of constitutive resistance to white pine weevil in Picea glauca-engelmannii (Interior spruce)
White pine weevil is a major pest of conifers in North America, especially for Spruce trees. Constitutive defenses are important in understanding defense mechanisms because they constitute the initial barrier to attacks by weevils and other pests. Resistant and susceptible trees exhibit constitutive...
ORGANISM(S): Picea engelmannii x Picea glauca 
2011-11-28 | E-GEOD-27476 | biostudies-arrayexpress
UnknownUsing PVA and captive breeding to balance trade-offs in the rescue of the island dibbler onto a new island ark.
Not available
S-EPMC9279492 | biostudies-literature
ProteomicsElucidating the role of bacteriophage lifestyle strategy in Microbially-Mediated Perennial Rhizosphere Nitrogen Transformations
Illumination of the interplay between viral community lifestyle strategy (lytic vs. temperate) and the impact of these interactions on microbial population dynamics and metabolic functioning in soil is critical to our understanding of bioenergy crop productivity as well as carbon and nitrogen cyclin...
ORGANISM(S): Soil Microbiome 
2025-04-24 | MSV000097724 | MassIVE
TranscriptomicsInterior Spruce_Bark_PissodesStrobi _Herbivory
We performed a transcriptome analysis of interior spruce (Picea glauca x engelmannii) bark response to weevil (Pissodes strobi) feeding using 21.8K spruce microarray (that contains 21.8 thousand unique transcripts). This microarray study revealed a large rearrangement of the interior spruce bark tra...
ORGANISM(S): Picea engelmannii x Picea glauca 
2012-12-01 | E-GEOD-23715 | biostudies-arrayexpress
TranscriptomicsGene expression during seed coat development in Arabidopsis
Transcriptional profiling during Arabidopsis seed coat development at 3 key developmental timepoints by using 2 mutant lines and their wild types. The data provides a globe view of seed coat development in arabidopsis can be used for identification of new gene candidates for seed coat development. 3...
ORGANISM(S): Arabidopsis thaliana 
2011-03-10 | E-GEOD-27857 | biostudies-arrayexpress
TranscriptomicsRNAseq of small intestinal organoids from mice treated with the cytokines IL-13 and IL-22 for 72 hours in combination with the BMP signaling inhibitor DMH1
The intestinal epithelium is our first line of defense against infections of the gut and the plasticity in cellular differentiation of the intestinal epithelium is an important part of this response. The changes in cellular composition is driven by immune cell derived cytokines. Here we use signatur...
ORGANISM(S): Mus musculus 
2022-05-08 | E-MTAB-9185 | biostudies-arrayexpress
ProteomicsLabel-free global proteome profiling of European American and African American bladder tumor patients.
Bladder cancer (BLCA) mortality is higher in African American (AA) patients compared to their European American (EA) counterparts, but the molecular mechanism underlying differences are unknown. . Thus, we performed proteomics analysis of AA and EA BLCA and identified higher mitochondrial OXPHOS spe...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-08-08 | MSV000095559 | MassIVE
TranscriptomicsPeripheral Blood Cells Gene Expression Profiles from Discordant Monozygotic Twins with Systemic Autoimmune disease (SAIDs)
Gene expression profiling in peripheral blood cells from monozygotic twin pairs with various sytemic autoimmune diseases revealed 92 genes that could discriminate between MZ twin pairs and unrelated-matched controls. No genes were found that could discriminate between proband and unaffected twin pai...
ORGANISM(S): Homo sapiens 
2010-12-30 | E-GEOD-24060 | biostudies-arrayexpress
TranscriptomicsOscillations in supercoiling drive circadian gene expression in cyanobacteria
The cyanobacterium Synechococcus elongatus PCC 7942 exhibits oscillations in mRNA transcript abundance with 24-hour periodicity under continuous light conditions. The mechanism underlying these oscillations remains elusive â?? neither cis nor trans-factors controlling circadian gene expression phase...
ORGANISM(S): Synechococcus elongatus PCC 7942 
2010-05-19 | E-GEOD-18902 | biostudies-arrayexpress
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