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TranscriptomicsExpression Data from Bone Marrow Progenitor-Derived Adipocytes, White Adipocytes and Brown Adipocytes.
We have identified a population of adipocytes in fat tissue that arise from bone marrow-derived progenitor cells. We used microarrays to compare the global gene expression patterns of the bone marrow progenitor-derived adipocytes as well as conventional white and brown adipocytes to evaluate the rel...
ORGANISM(S): Mus musculus 
2010-01-08 | E-GEOD-19757 | biostudies-arrayexpress
MetabolomicsNitrate-Sialin2 Axis Couples ER-Mitochondrial Calcium Signaling with Fatty Acid Metabolism to Drive White Adipose Browning
Nutrient cues shape adipose homeostasis; however, the mechanism by which inorganic signals engage organelle networks to drive white fat browning remains unclear. Here, we identify a nitrate-Sialin2 pathway that converts dietary nitrate into a spatially confined thermogenic program. Sialin2 localizes...
2026-05-17 | MTBLS14192 | MetaboLights
MetabolomicsData on changes in lipid profiles during differentiation and maturation of human subcutaneous white adipocytes analyzed using chromatographic and bioinformatics tools
Not available
ORGANISM(S): Homo sapiens 
ST001958 | MetabolomicsWorkbench
TranscriptomicsWhite-to-brown metabolic conversion of human adipocytes by JAK inhibition
The rising incidence of obesity and related disorders such as diabetes and heart disease has focused considerable attention on the discovery of novel therapeutics. One promising approach has been to increase the number or activity of brown-like adipocytes in white adipose depots, as this has been...
ORGANISM(S): Homo sapiens 
2014-10-31 | E-GEOD-57896 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse brown and white adipocyte differentiated and undifferentiated states
Attainment of a brown adipocyte cell phenotype in white adipocytes, with their abundant mitochondria and increased energy expenditure potential, is a legitimate strategy for combating obesity. The unique transcriptional regulators of the primary brown adipocyte phenotype are unknown, limiting our ab...
ORGANISM(S): Mus musculus 
2009-04-08 | E-GEOD-7032 | biostudies-arrayexpress
TranscriptomicsGW7647 and Rosiglitazone treated human differentiated adipocytes
Objective : This work aimed at characterizing PPARα involvement in metabolism regulation and at comparing PPARα and PPARγ roles in human white adipocytes. Research Design and Methods : Profiling of gene expression alterations was assessed with microarrays and RT-qPCR. Primary cultures of human adipo...
ORGANISM(S): Homo sapiens 
2010-04-11 | E-GEOD-15862 | biostudies-arrayexpress
ProteomicsComparative secretome analysis of primary murine white and brown adipocytes
The adipose organ, including white and brown adipose tissues, is an important player in systemic energy homeostasis, storing excess energy in form of lipids while releasing energy upon various energy demands. Recent studies have demonstrated that white and brown adipocytes also function as endocrine...
ORGANISM(S): Mus musculus (Mouse) 
2018-09-04 | PXD009280 | Pride
Brown adipocytes Adrenergic stimulation White adipocytes Secretome Murine svf cells 
ProteomicsAdaptation of white adipocytes to cooler temperatures: adipocytes cultured at either 37°C or 31°C
This study investigates how differentiated white adipocytes adapt to cooler temperatures by remodeling their acetyl-lysine–modified proteome. Differentiated adipocytes were cultured at 37°C or 31°C for 12 days to induce temperature-dependent physiological and biochemical changes. To profile acetylat...
ORGANISM(S): Mus musculus (Mouse) 
2026-09-07 | PXD079423 | Pride
Adipocytes cultured at either 37°c or 31°c Acetyl‑lysine proteomics 
ProteomicsData on the change in the protein profiles of human subcutaneous white adipocytes during differentiation and maturation
We analyzed changes in the protein profiles that occur during differentiation and maturation of cultured human subcutaneous white preadipocytes. We divided the three cell lines (Cell Line-1, Cell Line-2, and Cell Line-3) of Caucasian-derived subcutaneous preadipocytes into five stages: i) subcutaneo...
ORGANISM(S): Homo Sapiens (human) 
2022-07-04 | PXD035060 | JPOST Repository
TranscriptomicsRNA-seq comparison of primary mouse classical brown, beige, and white adipocytes
Classical brown adipocytes in interscapular BAT (Myf-5 derived) and inducible beige cells in WAT (non-Myf-5 derived) have distinct developmental origins, although both cell types have morphological and biochemical characteristics of brown fat such as the expression of UCP1. This raises an important ...
ORGANISM(S): Mus musculus 
2015-03-16 | E-MTAB-2624 | biostudies-arrayexpress
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