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ProteomicsB7-H4 post-translational modifications
B7-H4 functions as an immune checkpoint in the tumor microenvironment (TME). However, the post-translational modification (PTM) of B7-H4 and its translational potential in cancer remains incompletely understood. We found that ZDHHC3, a zinc finger DHHC-type palmitoyltransferase, palmitoylates B7-H4 ...
ORGANISM(S): Homo sapiens (Human) 
2025-02-14 | PXD054393 | Pride
Lysosome Palmitoylation Breast cancers Abemaciclib B7-h4 
TranscriptomicsSingle cell RNA-seq of an native and engineered metastatic niche in a metastatic breast cancer murine model
Metastatic lesions are typically not found until patients self-report symptoms or they become radiologically evident. We have developed an engineered metastatic niche (scaffold) that recruits aggressive tumor cells prior to their colonization in other organs. The engineered niche can be monitored fo...
ORGANISM(S): Mus musculus 
2022-08-02 | E-MTAB-8503 | biostudies-arrayexpress
UnknownFlower lose, a cell fitness marker, predicts COVID-19 prognosis.
Not available
S-EPMC8573598 | biostudies-literature
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