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ModelsMammalian Cell Cycle
BACKGROUND: In breast cancer, overexpression of the transmembrane tyrosine kinase ERBB2 is an adverse prognostic marker, and occurs in almost 30% of the patients. For therapeutic intervention, ERBB2 is targeted by monoclonal antibody trastuzumab in adjuvant settings; however, de novo resistance to t...
1607 | Cell Collective
UnknownModeling ERBB receptor-regulated G1/S transition to find novel targets for de novo trastuzumab resistance.
Not available
S-EPMC2652436 | biostudies-literature
MetabolomicsGNPS Fusarium
Co culture experiment with F. fujikuroi and R. s. media
ORGANISM(S): Ralstonia Solanacearum (ncbitaxon:305) Fusarium Fujikuroi (ncbitaxon:5127) 
2017-02-09 | MSV000080540 | GNPS
UnknownNotch-Mediated Tumor-Stroma-Inflammation Networks Promote Invasive Properties and CXCL8 Expression in Triple-Negative Breast Cancer.
Not available
S-EPMC6492532 | biostudies-literature
UnknownTumor-Stroma-Inflammation Networks Promote Pro-metastatic Chemokines and Aggressiveness Characteristics in Triple-Negative Breast Cancer.
Not available
S-EPMC6473166 | biostudies-literature
UnknownA surface-exposed GH26 β-mannanase from Bacteroides ovatus: Structure, role, and phylogenetic analysis of BoMan26B.
Not available
S-EPMC6556568 | biostudies-literature
TranscriptomicsTKI258_FGFR_INHIBITOR_TREATMENT
New targets and drugs for treatment of breast cancer are needed. We tested the effects of the TKI258 (Novartis) FGFR-inhibitor on tumor formation in mice. 4T1 mouse cell line, which had been derived from BALB/c mice, was injected into tail veins of BALB/c mice (syngraft model). Seven days later, mic...
ORGANISM(S): Mus musculus 
2013-02-17 | E-MTAB-1260 | biostudies-arrayexpress
UnknownPhylogenetic and physiological signals in metazoan fossil biomolecules.
Not available
S-EPMC7439315 | biostudies-literature
TranscriptomicsRNA-seq analysis of primary human cancer associated fibroblasts isolated from breast cancer tissue
Primary human cancer associated fibroblasts (CAFs) were isolated and cultivated (up to passage 10). CAFs were sequenced to find differences in their respective gene expression patters.
ORGANISM(S): Homo sapiens 
2021-02-03 | E-MTAB-10075 | biostudies-arrayexpress
UnknownPro-Inflammatory versus Immunomodulatory Effects of Silver Nanoparticles in the Lung: The Critical Role of Dose, Size and Surface Modification.
Not available
S-EPMC5666465 | biostudies-literature
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