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MetabolomicsMetabolic Biomarkers of Ageing in C57BL/6J Wild-Type and Flavin-Containing Monooxygenase 5 (FMO5)-Knockout Mice
It was recently demonstrated in mice that knockout of the flavin-containing monooxygenase 5 gene, Fmo5, slows metabolic ageing via pleiotropic effects. We have now used an NMR-based metabonomics approach to study the effects of ageing directly on the metabolic profiles of urine and plasma from male,...
2018-06-20 | MTBLS667 | MetaboLights
GenomicsAstrocyte mRNA expression - comparison of wild type animals to CETP transgenic animals
Astrocyte mRNA expression - comparison of wild type animals to CETP transgenic animals
PRJNA436339 | ENA
TranscriptomicsMicroarray analysis of TAP::ALG-1 associated RNAs isolated from synchronized 'wild-type' animals and 'mir-58' mutants
To discover new miRNA targets, we generated a C. elegans transgenic line expressing a functional N-terminally Tandem Affinity Purification (TAP) tagged ALG-1 protein (C. elegans strain WS4303). We crossed the TAP::ALG-1 transgene into the mir-58(n4640) mutant background to generate the strain WS5041...
ORGANISM(S): Caenorhabditis elegans 
2012-03-01 | E-GEOD-32942 | biostudies-arrayexpress
TranscriptomicsExpression from C. elegans L4 animals
Nutrient-driven O-GlcNAcylation of key components of the transcription machinery may epigenetically modulate gene expression in metazoans. Knockouts of the O-GlcNAc cycling enzymes in C. elegans are viable and fertile, allowing a global analysis of the impact of GlcNAcylation. Whole genome transcrip...
ORGANISM(S): Caenorhabditis elegans 
2010-01-01 | E-GEOD-18131 | biostudies-arrayexpress
GenomicsGenomic characterization of Listeria spp. from wild animals in Spain
Genomic characterization of Listeria spp. from wild animals in Spain
PRJEB41942 | ENA
TranscriptomicsExpression from C. elegans L1 animals
Nutrient-driven O-GlcNAcylation of key components of the transcription machinery may epigenetically modulate gene expression in metazoans. Knockouts of the O-GlcNAc cycling enzymes in C. elegans are viable and fertile, allowing a global analysis of the impact of GlcNAcylation. Whole genome transcrip...
ORGANISM(S): Caenorhabditis elegans 
2009-12-31 | E-GEOD-18130 | biostudies-arrayexpress
GenomicsCervus elaphus elaphus strain:Wild animals-game
Cervus elaphus elaphus, Capreolus capreolus, Dama dama, Ovis aries musimon, Sus scrofa scrofa APVV-0368-10: Multiplex molecular genetic analyses for identification of unknown biological samples from free living animals
PRJNA167964 | ENA
TranscriptomicsTranscriptional profiling of nhr-114 vs. glp-1 animals, and wild type + Trp vs. wild type animals.
Animals can thrive on variable food resources as a result of autonomous processes and beneficial relationships with their gut microbes. Food intake elicits major physiological changes, which are compensated with transient systemic responses that maintain homeostasis in the organism. This integration...
ORGANISM(S): Caenorhabditis elegans 
2013-03-01 | E-GEOD-43864 | biostudies-arrayexpress
TranscriptomicsPurification of TAP::ALG-1 complexes and associated RNA from mixed-stage TAP::ALG-1 transgenic (WS4303) and wild-type (N2) animals
To discover new miRNA targets, we generated a C. elegans transgenic line expressing a functional N-terminally Tandem Affinity Purification (TAP) tagged ALG-1 protein We purified TAP::ALG-1 complexes from mixed-stage TAP::ALG-1 transgenic (WS4303) and wild-type (N2, serving as a mock control) animals...
ORGANISM(S): Caenorhabditis elegans 
2012-03-01 | E-GEOD-32941 | biostudies-arrayexpress
ProteomicsHemolymph protein signatures in wild and farmed crayfish
The aim of the present study was to carry out a high-throughput proteomics analysis of the hemolymph from wild and captive crayfish to detect the list of proteins that orchestrate adaptations of animals to different environments.
ORGANISM(S): Procambarus virginalis 
2026-07-31 | PXD074479 | Pride
Wild Hemolymph Environment Farmed Protein Crayfish 
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