Willems Christophe C

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Transcriptomics (2)
Unknown (2)
Proteomics (2)

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Homo sapiens (2)
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Repository

biostudies-arrayexpress (2)
pride (2)

Tissue

Tear (2)

Disease

Aniridia (2)

Technology Type

Bottom-up proteomics (2)
Data-independent acquisition (2)
Mass Spectrometry (2)

Publication Date

2015 (2)
2026 (2)

Study type

Transcription profiling by array (2)

Release Date

2015 (2)
2020 (1)
2014 (1)

Lab affiliation

LBPC-PPC, Montpellier University, IRMB CHU Montpellier, INM INSERM, Montpellier, Occitanie, France (2)

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Pituitary tumors contain a (CD31¯/CD45¯ purified) side population with 'tumor stem cell'-associated characteristics [set 2]

Pituitary adenomas cause significant endocrine and mass-related morbidity. Not much is known about mechanisms underlying pituitary tumor pathogenesis. We searched for a side population (SP) in pituitary tumor, representing cells with high efflux capacity and potentially enriching for cancer/tumor st...

ORGANISM(S): Homo sapiens

2015-08-04 | E-GEOD-62870 | biostudies-arrayexpress

Pituitary tumors contain a side population with 'tumor stem cell'-associated characteristics [set 1]

Pituitary adenomas cause significant endocrine and mass-related morbidity. Not much is known about mechanisms underlying pituitary tumor pathogenesis.We searched for a side population (SP) in pituitary tumor, representing cells with high efflux capacity and potentially enriching for cancer/tumor ste...

ORGANISM(S): Homo sapiens

2015-08-04 | E-GEOD-62866 | biostudies-arrayexpress

Comparative analysis of tear proteomics in PAX6 mutant and control mice of both sexes before and after abrasion

Our team is working on aniridia, an autosomal dominant condition and has used a mouse model. The cornea, the eye’s first avascular and transparent optical surface, is covered by a stratified epithelium that constantly renews itself; any disruption compromises transparency and threatens vision. The t...

ORGANISM(S): Mus musculus (Mouse)

2026-06-01 | PXD070553 | Pride

PLAPAX6: Proteomic study of tears from patients with a PAX6 mutation

The cornea is the eye’s first optical surface, avascular and transparent, covered externally by a stratified epithelium that constantly renews itself. Disruption in this renewal compromises transparency, potentially leading to vision loss. The corneal surface is protected and nourished by the tear f...

ORGANISM(S): Homo sapiens (Human)

2026-09-07 | PXD066455 | Pride

Pax6 Aniridia Tears proteomic

Liver-specific transcriptional modules identified by genome-wide in silico analysis enable efficient gene therapy in mice and non-human primates.

Not available

S-EPMC4435486 | biostudies-literature

De Novo Variants in CNOT1, a Central Component of the CCR4-NOT Complex Involved in Gene Expression and RNA and Protein Stability, Cause Neurodevelopmental Delay.