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TranscriptomicsExpression profiling in Williams-Beuren Syndrome patient fibroblast cell lines
Williams-Beuren Syndrome (WBS) is a neurodevelopmental disorder caused by aa 1.5 Mb microdeletion on human chromosome 7. Although the molecular cause of the disorder is well-established, little is known about the global impact of the deletion on gene expression. Here we profiled the transcriptomes o...
ORGANISM(S): Homo sapiens 
2011-01-31 | E-GEOD-16715 | biostudies-arrayexpress
TranscriptomicsThe unique molecular signature of cortical tissue injury in Multiple Sclerosis
In the present study we addressed several questions related to the mechanisms of cortical injury. We analyzed genome wide gene expression by microarrays, comparing active multiple sclerosis lesions with highly inflammatory lesions of chronic tuberculous meningitis, with neurodegenerative lesions of ...
ORGANISM(S): Homo sapiens 
2011-10-05 | E-GEOD-32645 | biostudies-arrayexpress
GenomicsDDM1 and RdDM are the major regulators of transposon DNA methylation in Arabidopsis
Eukaryotic DNA methylation is found in silent transposable elements and active genes. Nucleosome remodelers of the DDM1/Lsh family are thought to be specifically required to maintain transposon methylation, but the reason for this is unknown. Here, we find that a chromatin gradient that extends from...
ORGANISM(S): Arabidopsis thaliana 
2013-04-17 | E-GEOD-41302 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Salmonella enterica serotype SL1344 wildtype, pSf-R27sfh and pSf-R27 at stationary and exponential growth phases, to investigate the role of the Sfh protein encoded by transmissible plasmids and involved in human typhoid
The Sfh protein is encoded by self-transmissible plasmids involved in human typhoid and is closely related to the global regulator H-NS. We have found that Sfh provides a stealth function that allows the plasmids to be transmitted to new bacterial hosts with minimal effects on their fitness. Introdu...
ORGANISM(S): Salmonella enterica serotype Typhimurium 
2007-01-15 | E-SGRP-7 | biostudies-arrayexpress
TranscriptomicsThe effect of loss of Makibishi1-(MKB1) function on the transcriptome of Medicago truncatula hairy roots
RNA-Seq analysis on Medicago truncatula hairy roots, either control lines or lines silenced for the Makbishi1 (MKB1) gene, grown in either mock conditions or elicited with the plant stress hormone methyl jasmonate for 4 hours
ORGANISM(S): Medicago truncatula 
2022-05-07 | E-MTAB-11668 | biostudies-arrayexpress
TranscriptomicsLoor-Mouse-mammary transcriptomics
Effect of supplemental trans-10,cis-12-CLA during lactation on mammary tissue gene expression profiles.
ORGANISM(S): Mus musculus 
2012-07-28 | E-MEXP-3622 | biostudies-arrayexpress
UnknownComparative effectiveness of immediate antiretroviral therapy versus CD4-based initiation in HIV-positive individuals in high-income countries: observational cohort study.
Not available
S-EPMC4643831 | biostudies-literature
TranscriptomicsChromatin immunoprecipitation of human SKBR3 cells using anti-p53 antibodies
ChIP with anti-p53 (DO-1) of human SKBR3 cells
ORGANISM(S): Homo sapiens 
2010-02-18 | E-MEXP-2538 | biostudies-arrayexpress
Genomics8f81ce09-cd65-468c-a27a-d4f4863b24c4 - samples
The data are the aggregate results from an IGPP Consortium genome-wide survival study, showing overall risk for Parkinson disease progression associated with each variant in a longitudinal cohort study. 11.2 million deeply imputed variants in 3,821 PD patients who were prospectively tracked with 36,...
EGAD00001007060 | EGA
GenomicsInternational Genetics of Parkinson Disease Progression (IGPP) Consortium GWAS Summary Results
To characterize how genetic variation influences the progression of Parkinson’s disease to dementia, which is a major determinant for quality of life, we performed a longitudinal genome-wide survival study (GWSS). Risk profile analysis was performed with a novel polygenic hazard score in longit...
EGAS00001005110 | EGA
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