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TranscriptomicsTranscription profiling of human monocytic cells THP-1 stimulated with LPS (10ng/ml) in presence or absence of LL-37 (5 ug/ml), as well as with the peptide alone, for 4 hours
The objective of the study was to evaluate transcriptional response of endotoxin-stimulated human monocytic cells in presence or absence of host defense peptide LL-37 at low physiologically relevant concentrations. Human monocytic cells THP-1 were stimulated with LPS (10ng/ml) in presence or absenc...
ORGANISM(S): Homo sapiens 
2006-12-07 | E-FPMI-6 | biostudies-arrayexpress
TranscriptomicsChromatin immunoprecipitation of wild type, SET2 deletion, Rco1 PHD domain deletion and Eaf3 chromodomain deletion yeast using anti-acetyl-histone H4
Nucleosomes must be deacetylated behind elongating RNA polymerase II to prevent cryptic initiation of transcription within the coding region. RNA polymerase II signals for deacetylation through methylation of histone H3 lysine 36 (H3K36) which provides the recruitment signal for the Rpd3S deacetylas...
ORGANISM(S): Saccharomyces cerevisiae 
2007-05-16 | E-TABM-260 | biostudies-arrayexpress
UnknownVenue-Mediated Weak Ties in Multiplex HIV Transmission Risk Networks Among Drug-Using Male Sex Workers and Associates.
Not available
S-EPMC4431095 | biostudies-literature
Transcriptomics17b-Trenbolone study
We investigated the genomic transcriptional response of female fathead minnows (Pimephales promelas) to an acute (4 day) exposure to 0.1 or 1.0 µg/L of, 17β-trenbolone (TB), the active metabolite of an anabolic androgenic steroid used as a growth promoter in cattle and a contaminant of concern in ...
ORGANISM(S): Pimephales promelas 
2010-05-14 | E-GEOD-12904 | biostudies-arrayexpress
TranscriptomicsTet1 and hydroxymethylcytosine in transcription and DNA methylation fidelity (Affymetrix gene expression data)
Enzymes catalyzing the methylation of the 5-position of cytosine (mC) have essential roles in regulating gene expression, genome stability, and maintaining cellular identity. Recently Tet1, which is highly expressed in embryonic stem (ES) cells, was found to oxidize the methyl group of mC converting...
ORGANISM(S): Mus musculus 
2011-04-13 | E-GEOD-24842 | biostudies-arrayexpress
TranscriptomicsTranscription profiling time series of Candida albicans treated with different doses of acetic acid
Wild type Candida albicans (CAI8 containing CIp10) cultures were grown in triplicate at 1 x 107 cells ml-1 in 50 ml SC-pH3.0 broth. Cultures were then treated with 0, 20, 120 or 300
mM acetic acid. Cells were harvested after zero, 10, 30, 60, 120, 210 and 300 min treatment. RNA isolated from tri...
ORGANISM(S): Candida albicans 
2008-07-31 | E-MEXP-1645 | biostudies-arrayexpress
TranscriptomicsTranscription profiling wild type C. albicans after treatment with stress-inducing doses of acetic acid
Transcript profiling was performed using a wild-type C. albicans strain (CaI8+CIp10). Cells were cultured in 50 ml SC-pH3.0 to a cell density of 1x10^7 cells per ml and then either treated with control (0 mM acetic acid) or stress inducing (20 mM acetic acid) doses. Cells from the same culture were ...
ORGANISM(S): Candida albicans 
2008-07-31 | E-MEXP-1633 | biostudies-arrayexpress
TranscriptomicsExtensive demethylation of repetitive elements during seed development underlies gene imprinting
DNA methylation is an epigenetic mark associated with transposable element silencing and gene imprinting in flowering plants and mammals. In plants, imprinting occurs in the endosperm, which nourishes the embryo during seed development. We have profiled Arabidopsis DNA methylation genome-wide in the...
ORGANISM(S): Arabidopsis thaliana 
2009-06-12 | E-GEOD-14570 | biostudies-arrayexpress
TranscriptomicsMulti-component epigenetic control of pro-invasive genes in cancer cells
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2010-01-05 | E-GEOD-18899 | biostudies-arrayexpress
TranscriptomicsBrd4 and JMJD6-associated Anti-pause Enhancers in Regulation of Transcriptional Pause Release
Distal enhancers characterized by H3K4me1 mark play critical roles in developmental and transcriptional programs. However, potential roles of specific distal regulatory elements in regulating RNA Polymerase II (Pol II) promoter-proximal pause release remain poorly investigated. Here we report that a...
ORGANISM(S): Homo sapiens 
2014-01-14 | E-GEOD-51633 | biostudies-arrayexpress
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