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TranscriptomicsImplications of high level pseudogene transcription in Mycobacterium leprae
Approximately half of M. lepraeâ??s transcriptome consists of inactive gene products. This has an impact on overall energy and resource consumption without potential benefit to this organism. However, multiple translational â??silencingâ?? mechanisms are present, reducing additional energy and resou...
ORGANISM(S): Mycobacterium leprae 
2010-06-24 | E-GEOD-17191 | biostudies-arrayexpress
TranscriptomicsSeasonal Changes in Patterns of Gene Expression in Avian Song Control Brain Regions
Photoperiod and hormonal cues drive dramatic seasonal changes in structure and function of the avian song control system. Little is known, however, about the patterns of gene expression associated with seasonal changes. Here we address this issue by exposing GambelM-bM-^@M-^Ys white-crowned sparrows...
ORGANISM(S): Taeniopygia guttata 
2012-10-01 | E-GEOD-28347 | biostudies-arrayexpress
UnknownA Century of Shope Papillomavirus in Museum Rabbit Specimens.
Not available
S-EPMC4493010 | biostudies-literature
TranscriptomicsMouse CD4+/CD8+ thymocytes from miR-181a1/b1 KO vs WT
miR-181a1/b1, miR-181a2/b2, and miR-181c/d belong to a highly conserved family of microRNA clusters, yet their role in vivo is poorly understood. Here we show that the miR-181a1/b1 cluster is absolutely essential for NKT development and is a critical determinant of thymocyte proliferation, survival ...
ORGANISM(S): Mus musculus 
2014-04-09 | E-GEOD-41090 | biostudies-arrayexpress
MetabolomicsIntegrated Exposomics/Metabolomics for Rapid Exposure and Effect Analyses

The totality of environmental exposures and lifestyle factors, commonly referred to as the exposome, are poorly understood. Measuring the myriad of chemicals that humans are exposed to is immensely challenging and identifying disrupted metabolic pathways is even more complex. Here, we present a n...

2023-10-26 | MTBLS4556 | MetaboLights
TranscriptomicsChromatin immunoprecipitation of Foxp3 in mouse T-cell hybridoma cells
The forkhead transcription factor Foxp3 is essential for the development of CD4+CD25+ regulatory T (Treg) cells and prevention of autoimmunity, but how it controls the Treg gene expression program is not understood. We describe here genome-wide location and expression data that identify Foxp3 targe...
ORGANISM(S): Mus musculus 
2007-01-27 | E-TABM-154 | biostudies-arrayexpress
UnknownClinical utility of random anti-tumor necrosis factor drug-level testing and measurement of antidrug antibodies on the long-term treatment response in rheumatoid arthritis.
Not available
S-EPMC4843946 | biostudies-literature
GenomicsGoT2D: Genetics of Type 2 Diabetes, a study of the the genetic architecture of type 2 diabetes using low pass whole genome sequencing and high density SNP genotyping in 2,657 individuals.
The Genetics of Type 2 Diabetes Consortium (GoT2D) is a collaboration between the University of Michigan, the Broad Institute and the Wellcome Trust Centre for Human Genetics. The overall aim is to extend upon recent efforts, such as genome-wide association studies (GWAS) and large scale meta-analys...
EGAS00001001459 | EGA
GenomicsGenome wide association scan in Parkinson's disease
Genome-wide association scan was performed in 1,705 cases of parkinson's genotyped on the Illumina Human 660W SNP array, and 5,175 controls genotyped on the Illumina1.2M-Duo. Analysis was carried out on the overlaps set of SNPs.
EGAS00000000034 | EGA
UnknownEffect of Four Hemoglobin Transfusion Threshold Strategies in Patients With Acute Myocardial Infarction and Anemia : A Target Trial Emulation Using MINT Trial Data.
Not available
S-EPMC12701713 | biostudies-literature
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