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ProteomicsA GABARAP−PtdIns3K-C1 positive feedback loop at the heart of the phagophore nucleation
Macroautophagy/autophagy is a cellular process enabling degradation of intracellular components during starvation. In mammalian cells, autophagosomes can reach diameters of over 1000 nm within 30 min after triggering starvation, but how such substantial amounts of membranes can be synthesized within...
ORGANISM(S): Homo sapiens (Human) 
2026-07-02 | PXD079187 | Pride
Structural characterization Pi3k Xl-ms Cryo-em Hdx-ms Autophagy 
ProteomicsA GABARAP−PtdIns3K-C1 positive feedback loop at the heart of the phagophore nucleation
Macroautophagy/autophagy is a cellular process allowing the degradation of intracellular components during starvation. In mammalian cells, autophagosomes can reach over 1000 nm within 30 min after triggering starvation, but how such substantial amounts of membranes can be synthesized within a brief ...
ORGANISM(S): Homo sapiens (Human) 
2026-07-02 | PXD074963 | Pride
Autophagy  cryo-em  gabarap  hdx-ms  lc3  positive feedback loop  xl-ms 
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