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ProteomicsQuantitative mass spectrometry analysis of 70S ribosomes from iSAT
The ribosome is one of the largest and the most complicated enzymes in cells, making up 25% of the bacterial cell’s dry mass, and is responsible for protein synthesis in all organisms on earth. In 2013, Jewett et al. reported an in vitro system named integrated rRNA synthesis, ribosome assembly, and...
ORGANISM(S): Escherichia coli 
2023-05-10 | PXD038716 | Pride
In vitro 70s Ribosome Lc-ms/ms 
ProteomicsAnti-sense oligonucleotide inhibited iSAT reaction
Investigating the intricate and rapid folding kinetics of large RNA-protein complexes (RNPs), like the bacterial ribosome, remains a formidable challenge in structural biology. Previous genetic approaches to probe assembly have focused on modulating the expression of either r-proteins or assembly fa...
ORGANISM(S): Escherichia coli 
2025-07-28 | PXD064127 | Pride
Sucrose gradient fractions Isat Ribosome biogenesis 
ProteomicsResource allocation in the archaeon Methanococcus maripaludis during slow growth
We conducted a systems-level study on the physiology of slow growth in the archaeon Methanococcus maripaludis revealing a strategy for acclimation to slow growth that relies on redistribution of energy for cellular maintenance and changes in catabolic and ribosomal activity rather than gene regulati...
ORGANISM(S): Methanococcus Maripaludis S2 (ncbitaxon:267377) 
2021-02-11 | MSV000086844 | MassIVE
ProteomicsPytheas SARS-CoV-2 spike protein mRNA sample analysis
Mass spectrometry remains an important method for analysis of modified nucleosides ubiquitously present in cellular RNAs, in particular for ribosomal and transfer RNAs that play crucial roles in mRNA translation and decoding. Furthermore, modifications have effect on the lifetimes of nucleic acids i...
ORGANISM(S): Escherichia coli 
2022-05-04 | PXD030845 | Pride
Isotope labeling Sars-cov-2 spike protein Pytheas Mrna 
ProteomicsRNA oligomers training set for the Pytheas scoring function
Mass spectrometry remains an important method for analysis of modified nucleosides ubiquitously present in cellular RNAs, in particular for ribosomal and transfer RNAs that play crucial roles in mRNA translation and decoding. Furthermore, modifications have effect on the lifetimes of nucleic acids i...
ORGANISM(S): Escherichia coli 
2022-05-04 | PXD030435 | Pride
Training set Scoring function Rna Pytheas 
ProteomicsPytheas S. cerevisiae 18S rRNA sample analysis
Mass spectrometry remains an important method for analysis of modified nucleosides ubiquitously present in cellular RNAs, in particular for ribosomal and transfer RNAs that play crucial roles in mRNA translation and decoding. Furthermore, modifications have effect on the lifetimes of nucleic acids i...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2022-05-04 | PXD030563 | Pride
Rna modifications Yeast Ribosome Pytheas 
ProteomicsPytheas E. coli 16S rRNA sample analysis
Mass spectrometry remains an important method for analysis of modified nucleosides ubiquitously present in cellular RNAs, in particular for ribosomal and transfer RNAs that play crucial roles in mRNA translation and decoding. Furthermore, modifications have effect on the lifetimes of nucleic acids i...
ORGANISM(S): Escherichia coli 
2022-05-04 | PXD030538 | Pride
16s Rna Ribosome Isotope labeling Pytheas 
UnknownCryoEM Dataset of L17-Depleted 50S Ribosomal Intermediates
Not available
EMPIAR-10076 | biostudies-other
UnknownMotion corrected micrographs - purified SINV/EEEV particles and recombinant anti-EEEV Fab (EEEV-33)
Not available
EMPIAR-10890 | biostudies-other
UnknownAge-related reduction in motor adaptation: brain structural correlates and the role of explicit memory.
Not available
S-EPMC7181181 | biostudies-literature
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