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MetabolomicsN6-methyladenosine modification is not a general trait of positive-sense RNA viral genomes

Despite the nuclear localization of the m6A machinery, the genomes of multiple exclusively-cytoplasmic RNA viruses, such as chikungunya (CHIKV) and dengue (DENV), are reported to be extensively m6A-modified. However, these findings are mostly based on m6A-seq, an antibody-dependent technique with...

2024-01-25 | MTBLS6978 | MetaboLights
ProteomicsUnbiased identification of Pleiotrophin-interacting proteins in the brain
Affinity purification-mass spectrometry was performed to identify proteins associated with pleiotrophin in wild-type mouse brain tissue. Ptn and hFc control pulldowns were analyzed to identify specific Ptn-interacting proteins.
ORGANISM(S): Mus musculus (Mouse) 
2026-07-21 | PXD081065 | Pride
Pleiotrophin  mouse brain 
ProteomicsProteomics Analysis of the Inferior Colliculus following Acute Hydrogen Sulfide
We used broad-spectrum proteomics to search for key molecules in H2S induced neurotoxicity. Mice were subjected to acute whole body exposure up to 750ppm of H2S at day1 for 40min, followed by 15min daily exposure. Following H2S exposure, inferior colliculi were harvested on day1, day2, and day4 and...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2017-10-26 | MSV000081650 | MassIVE
TranscriptomicsRTN1 IS A NOVEL MEDIATOR FOR PROGRESSION OF KIDNEY DISEASE
Gene expression profiling of kidneys from the murine model of HIV-associated nephropathy (HIVAN) identified an association between the expression of an endoplasmic reticulum (ER)-associated protein reticulon-1, RTN1, and the severity of kidney disease. Of the three known RTN1 isoforms, only RTN1A pr...
ORGANISM(S): Mus musculus 
2015-05-20 | E-GEOD-69074 | biostudies-arrayexpress
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