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MetabolomicsFirst-in-class MKK4 inhibitors enhance liver regeneration and prevent liver failure

Diminished hepatocyte regeneration is a key feature of acute and chronic liver diseases and after extended liver resections, resulting in the inability to maintain or restore a sufficient functional liver mass. Therapies to restore hepatocyte regeneration are lacking, making liver transplantation...

2024-09-23 | MTBLS9434 | MetaboLights
UnknownSeasonal variation of BMI at admission in German adolescents with anorexia nervosa.
Not available
S-EPMC6133390 | biostudies-literature
TranscriptomicsGSI, Human T-ALL
The NOTCH signaling cascade, which is deregulated in T-cell acute lymphoblastic leukemia (T-ALL) and many other human cancers, offers an attractive target for molecular therapy. One approach employs gamma-secretase inhibitors (GSIs) to suppress production of the intracellular form of NOTCH (NICD), ...
ORGANISM(S): Homo sapiens 
2010-05-27 | E-GEOD-8416 | biostudies-arrayexpress
ProteomicsTransfer of the high-quality sugar metabolic model of Aspergillus niger is reliable within the same fungal phylum, but limited for fungi of other phyla
Proteomic data from fungi; intracellular-proteome of five of the studied fungi (A. niger, A. nidulans, P. subrubescens, T. reesei and P. chrysosporium) grown on nine different monosaccharide conditions (L-arabinose, D-fructose, D-galacturonicAcid, D-galactose, D-glucuronicAcid, D-glucose, D-mannose,...
ORGANISM(S): Aspergillus Niger, Aspergillus Nidulans, Penicillium Subrubescens, Trichoderma Reesei, Phanerochaete Chrysosporium 
2022-10-05 | MSV000090477 | MassIVE
ProteomicsTransfer of the high-quality sugar metabolic model of Aspergillus niger is reliable within the same fungal phylum, but limited for fungi of other phyla
Validation of metabolic models, extrapolated from the reference sugar catabolism genetic network of Aspergillus niger by using an orthology-based approach, of evolutionarily diverse fungi.
ORGANISM(S): Trichoderma Reesei (ncbitaxon:51453) Penicillium Subrubescens (ncbitaxon:1316194) Aspergillus Niger (ncbitaxon:5061) Phanerochaete Chrysosporium Rp-78 (ncbitaxon:273507) Aspergillus Nidulans (ncbitaxon:162425) 
MSV000090441 | MassIVE
Genomicsena-DATASET-DKFZ-29-05-2020-15:56:12:496-205 - samples
ALI culture bronchial cells and alveolar lung surgical resection scRNA-Seq
EGAD00001006185 | EGA
2019 novel coronavirus infection 2019-nCoV infection coronavirus disease 2019 COVID-19 SARS-coronavirus 2 SARS-CoV-2 severe acute respiratory syndrome coronavirus 2 
GenomicsSARS‐CoV‐2 receptor ACE2 and TMPRSS2 are primarily expressed in bronchial transient secretory cells
The SARS‐CoV‐2 pandemic affecting the human respiratory system severely challenges public health and urgently demands for increasing our understanding of COVID‐19 pathogenesis, especially host factors facilitating virus infection and replication. SARS‐CoV‐2 was reported to enter cells via binding to...
EGAS00001004419 | EGA
2019 novel coronavirus infection 2019-nCoV infection coronavirus disease 2019 COVID-19 SARS-coronavirus 2 SARS-CoV-2 severe acute respiratory syndrome coronavirus 2 
GenomicsDAC for patient-derived cell line samples
Data Access Committee EGAC00001000594
EGAC00001000594 | EGA
Genomicsena-DATASET-DKFZ-IBIOS-12-04-2016-13:32:15:134-286 - samples
RNA sequencing data of whole blood samples from smoking and non-smoking mothers and their children at gestation/birth and follow-up years.
EGAD00001002011 | EGA
Genomicsena-DATASET-DKFZ-IBIOS-12-04-2016-13:35:10:904-287 - samples
ChIPseq data of whole blood samples from smoking and non-smoking mothers and their children at gestation/birth and follow-up years.
EGAD00001002012 | EGA
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