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This project or dataset comprises raw data of the proteome of different mutant strains of M. pneumoniae (∆mpn453; ∆mpn372; CV2 (∆mpn133∆mpn372); CV0 (WT_gp35) and ∆mpn133).The proteome of the strain was used to corroborate the genotype of the obtained mutants and to discard unspected changes in the ...
ORGANISM(S): Mycoplasma pneumoniae (strain ATCC 29342 / M129) 
2021-09-14 | PXD028011 | Pride
A robust predictor for hERG channel blockade based on an ensemble of five deep learning models. The authors have collected a dataset from public sources, such as BindingDB and ChEMBL on hERG blockers and non-blockers. The cut-off for hERG blockade was set at IC50 Model Type: Predictive machine lea...
2024-07-18 | MODEL2407180003 | BioModels
Analysis of gene expression profile of B16-F10 murine melanoma cells exposed to hypoxic conditions (1% oxygen) or hypoxia mimicry (cobalt chloride) for 24 hours. Gene expression profiles were analyzed using MG-U74Av2 oligonucleotide microarrays. Data analysis revealed 2541 probesets (FDR<5%) for 1...
ORGANISM(S): Mus musculus 
Total RNA was extracted from liver tissues of lab-reared threespine stickleback. First generation fish originating from the Baltic Sea near Helsinki (Finland) were bred using a paternal half-sib design. At 6 months individuals were randomly assigned to either a treatment or control group: the tem...
ORGANISM(S): Gasterosteus aculeatus 
OmpR is a DNA binding protein belonging to the OmpR/EnvZ two component system. This system is known to sense changes in osmolarity in Escherichia coli. Recently, OmpR in Salmonella enterica serovar Typhimurium was found to be activated by acidic pH and DNA relaxation. In this study, ChIP-on-chip wa...
ORGANISM(S): Escherichia coli K-12 
Penicillium marneffei (Talaromyces marneffei) is an opportunistic human pathogen that can grow in a multicellular hyphal form at 25M-BM-0C or a unicellular fission yeast form at 37M-BM-0C, and can switch between these two forms in response to temperature. The yeast form is found in infected individu...
ORGANISM(S): Talaromyces marneffei 
Exosomes (EXOs) are a biological subset of extracellular vesicles of 50-200 nm in size which are released by most cells upon fusion of multivehicular bodies with plasma membrane.Mimetic-Nanovesicles (M-NVs) have higher yield compare to exosomes. In addition, M-NVs can untangle the difficulties assoc...
ORGANISM(S): Homo sapiens (Human) 
2022-01-05 | PXD010539 | Pride
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