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TranscriptomicsQuantification of global transcription patterns in prokaryotes using spotted microarrays
We describe an analysis, applicable to any spotted microarray dataset produced using genomic DNA as a reference, which quantifies prokaryotic levels of mRNA on a genome-wide scale. Applying this to Mycobacterium tuberculosis, we validate the technique, show a correlation between level of expression...
ORGANISM(S): Mycobacterium bovis 
2008-09-30 | E-BUGS-60 | biostudies-arrayexpress
ProteomicsAutocatalytic activation of a malarial egress protease is druggable and requires a protein cofactor
Malaria parasite egress from host erythrocytes (RBCs) is regulated by discharge of a parasite serine protease called SUB1 into the parasitophorous vacuole (PV). There, SUB1 activates a PV-resident cysteine protease called SERA6, enabling host RBC rupture through SERA6-mediated degradation of the RBC...
ORGANISM(S): Plasmodium falciparum (isolate 3D7) 
2021-03-16 | PXD024084 | Pride
Lc-msms Malaria Protease Sub1 Sera6 
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