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TranscriptomicsTranscription profiling of human heat shocked HeLa cell line with siRNA knockdown of HSF1
Although HSF1 is known to play an important role in regulating the cellular response to proteotoxic stressors, little is known about the structure and function of the HSF1 signaling network under both stressed and unstressed conditions. In this study, we used a combination of chromatin immunoprecip...
ORGANISM(S): Homo sapiens 
2007-06-22 | E-GEOD-3697 | biostudies-arrayexpress
TranscriptomicsHeat shock experimental replicates
Heat stress experiments imposed on Buchnera aphidicola within intact Schizaphis graminum hosts. NOTE: normalized values in GEO are NOT those derived from intensive analyses described in paper. Please see Wilcox et al. 2002 for description. Keywords = reduced bacterial genome, stress response
ORGANISM(S): Buchnera aphidicola (Schizaphis graminum) 
2003-01-20 | E-GEOD-87 | biostudies-arrayexpress
TranscriptomicsMaternal influences on the transmission of leukocyte gene expression profiles in population samples (mother and child)
This study contrasts the expression profiles of peripheral blood leukocytes from third trimester pregnant mothers, with cord blood leukocytes from their newborn children. It is a companion to (GSE21311). After normalization for RNA integrity, major principal components of the variation were found ...
ORGANISM(S): Homo sapiens 
2011-01-01 | E-GEOD-21342 | biostudies-arrayexpress
no omics definedTranscription profiling of rat liver and kidney samples performed in 16 different institutions to determine study factors which are key sources of variability. Raw files available as additional archives.
BACKGROUND: The use of gene expression profiling in both clinical and laboratory settings would be enhanced by better characterization of variance due to individual, environmental, and technical factors. Meta-analysis of microarray data from untreated or vehicle-treated animals w...
ORGANISM(S): Rattus norvegicus 
2008-10-10 | E-TOXM-39 | biostudies-arrayexpress
TranscriptomicsmRNA Sequencing Reveals Altered Synaptic Vesicular Transport in Post-Mortem Cerebellum
Schizophrenia (SCZ) is a common, disabling mental illness with high heritability but complex, poorly understood genetic etiology. As the first phase of a genomic convergence analysis of SCZ, we generated 16.7 billion nucleotides of short read, shotgun sequences of cDNA from post-mortem cerebellar c...
ORGANISM(S): Homo sapiens 
2009-08-29 | E-GEOD-12297 | biostudies-arrayexpress
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