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ProteomicsQuantitative phosphoproteomic analysis of acquired drug resistance to pazopanib and dasatinib
Acquired drug resistance and tumour relapse impacts the majority of patients being treated with tyrosine kinase inhibitors (TKIs) and remains a key challenge in modern anti-cancer therapy. The lack of clinically effective therapeutic strategies to overcome drug resistance represents a significant un...
ORGANISM(S): Homo sapiens (Human) 
2017-08-30 | PXD005536 | Pride
Resistance Dasatinib Pazopanib A204 Phosphoproteomics 
UnknownFertility protection during chemotherapy treatment by boosting the NAD(P)+ metabolome.
Not available
S-EPMC11473878 | biostudies-literature
UnknownClinical and Genomic Characterization of Treatment-Emergent Small-Cell Neuroendocrine Prostate Cancer: A Multi-institutional Prospective Study.
Not available
S-EPMC6366813 | biostudies-literature
UnknownInsurance Denial of Biologic Therapy is Associated With Reduced Remission Rates in Inflammatory Bowel Disease Patients.
Not available
S-EPMC12277724 | biostudies-literature
UnknownTreatment of Recurrent Refractory Pediatric Pre-B Acute Lymphoblastic Leukemia Using Inotuzumab Ozogamicin Monotherapy Resulting in CD22 Antigen Expression Loss as a Mechanism of Therapy Resistance.
Not available
S-EPMC7216755 | biostudies-literature
UnknownFollicular lymphoma in the United States: first report of the national LymphoCare study.
Not available
S-EPMC2738614 | biostudies-literature
UnknownSelf-harm in 5-to-24 year olds: Retrospective examination of hospital presentations to emergency departments in New South Wales, Australia, 2012 to 2020.
Not available
S-EPMC10414637 | biostudies-literature
TranscriptomicsGene Expression in Castration-Resistant C4-2 Cells after AR Knockdown
Prostate cancer is the most common, lethal malignancy in men. Although androgen withdrawal therapies are used to treat advanced disease, progression to a castration-resistant, end-stage is the usual outcome. In this study, the tested hypothesis was that the androgen receptor remains essential for th...
ORGANISM(S): Homo sapiens 
2010-06-23 | E-GEOD-13332 | biostudies-arrayexpress
GenomicsNational Cancer Institute Genome-Wide Association Study of Renal Cell Carcinoma

The National Cancer Institute (NCI) genome-wide association study (GWAS) of renal cell carcinoma (RCC) was conducted to investigate common genetic variants associated with RCC risk. The GWAS includes 1,453 RCC cases and 3,531 controls of European background from 4 studies (3 cohort, 1 case-con...

phs000351.v1.p1 | EGA
TranscriptomicsTranscription profiling of BRCA1 wild type and mutant human breast tumors to examine expression of ER-alpha
Looking at the expression of ER alpha in BRCA1 and mutant tumours
ORGANISM(S): Homo sapiens 
2007-11-22 | E-TABM-366 | biostudies-arrayexpress
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