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UnknownChromatin landscapes and genetic risk in systemic lupus.
Not available
S-EPMC5134118 | biostudies-literature
TranscriptomicsSalicylic acid-induced gene expression in wild-type Col-0 and mutant ube4 Arabidopsis thaliana plants
Activation of plant immunity is associated with dramatic transcriptome reprogramming to prioritise immune responses over normal cellular functions. Changes in gene expression are coordinated by the immune hormone salicylic acid (SA). Here we investigated the involvement of the E4 ubiquitin ligase UB...
ORGANISM(S): Arabidopsis thaliana 
2019-03-20 | E-MTAB-7369 | biostudies-arrayexpress
UnknownTelehealth exercise to Improve Physical function and frailty in patients with multiple myeloma treated with autologous hematopoietic Stem cell transplantation (TIPS): protocol of a randomized controlled trial.
Not available
S-EPMC9633031 | biostudies-literature
GenomicsRegulation of heterochromatic DNA replication by histone H3 lysine 27 methyltransferases
Multiple pathways prevent DNA replication from occurring more than once per cell cycle. These pathways block re-replication by strictly controlling the activity of pre-replication complexes, which assemble at specific sites in the genome called origins. Here we show that mutations in the homologous ...
ORGANISM(S): Arabidopsis thaliana 
2010-07-21 | E-GEOD-22411 | biostudies-arrayexpress
TranscriptomicsCritical Role of Sphingolipid Pathway Components in Murine Radiation-Induced Lung Injury: Protection by Sphingosine-1-Phosphate Analogues
Clinically significant radiation-induced lung injury (RILI) is associated with significant morbidity and mortality and a common toxicity in patients administered thoracic radiotherapy. While the molecular etiology of RILI is poorly understood, we previously characterized a murine model of RILI in wh...
ORGANISM(S): Mus musculus 
2010-11-17 | E-GEOD-25295 | biostudies-arrayexpress
ProteomicsIdentification and characterization of mutations in ZBTB33 in clonal hematopoiesis and myelodysplastic syndromes
Beauchamp EM, Leventhal M, Bernard E, Hoppe ER, Todisco G, Creignou M, Galli A, Castellano CA, McConkey M, Tarun A, Wong W, Schenone M, Stanclift C, Tanenbaum B, Malolepsza E, Nilsson B, Bick AG, Weinstock JS, Miller M, Niroula A, Dunford A, Taylor-Weiner A, Wood T, Barbera A, Anand S, Psaty BM, Des...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-04-26 | MSV000087304 | MassIVE
ProteomicsSystematic evaluation and modulation of HLA class I downregulation in Merkel cell carcinoma
Lee PC, Klaeger S, Le PM, Korthauer K, Cheng J, Wong A, Tarren A, Lemvigh C, Sarkizova S, Li L, Frost TC, Nomburg J, Liu X, Pomerance L, Doherty L, Witten E, Zhang W, Apffel A, Wallace L, Neuberg D, Olsen L, Thakuria M, Clauser K, Starrett G, Doench J, Buhrlage SJ, Carr SA, DeCaprio JA, Wu CJ, Keski...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-04-20 | MSV000087251 | MassIVE
TranscriptomicsExpression data from E11.5 mouse embryonic forelimbs - various mutant conditions or dissected limb domains
Sonic hedgehog (Shh) signals via Gli transcription factors to direct digit number and identity in the vertebrate limb. We have characterized the Gli-dependent cis-regulatory network through a combination of whole genome ChIP-on-chip and transcriptional profiling of the developing mouse limb. In this...
ORGANISM(S): Mus musculus 
2008-09-14 | E-GEOD-11063 | biostudies-arrayexpress
UnknownA novel transcriptional signature identifies T-cell infiltration in high-risk paediatric cancer.
Not available
S-EPMC10071693 | biostudies-literature
TranscriptomicsTranscription profiling of human liver to evaluation of RNA binding specificity of aminoglycosides with DNA microarrays
We have developed methods for using DNA array technology to probe the entire transcriptome to determine RNA-binding specificity of ligands. Two methods were investigated. In the first, the RNA-binding aminoglycoside antibiotic tobramycin was covalently linked to magnetic beads. The beads were bou...
ORGANISM(S): Homo sapiens 
2008-06-13 | E-GEOD-5111 | biostudies-arrayexpress
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