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TranscriptomicsA Global View of the Oncogenic Landscape in Nasopharyngeal Carcinoma:An Integrated Analysis at the Genetic and Expression Levels
Previous studies have reported that the tumour cells of nasopharyngeal carcinoma (NPC) exhibit both recurrent chromosome abnormalities and changes in the expression of numerous genes. However, it is not known to what extent changes in the copy number of individual genes are associated with the obser...
ORGANISM(S): Homo sapiens 
2012-12-10 | E-GEOD-34573 | biostudies-arrayexpress
TranscriptomicsDown-regulation of BLIMP1-alpha by the EBV oncogene, LMP1, disrupts the plasma cell differentiation program and prevents viral replication in B cells
In this study, we have investigated the effect of BLIMP1α on gene expression, cell differentiation and pathogenesis in normal human GC B cells using a non-viral vector based system Gene expression was compared among BLIMP1α, LMP1-transfected and control vector-transfected GC B cells from two patient...
ORGANISM(S): Homo sapiens 
2011-07-26 | E-GEOD-27670 | biostudies-arrayexpress
TranscriptomicsGene expression changes in subclones of a Burkitt lymphoma cell line with different patterns of EBV latent infection
In this study we have investigated the gene expression profiles of three different types of subclone all generated by single cell cloning of the same parental EBV positive Burkitt lymphoma cell line Awia-BL. These included EBV negative clones which have lost the virus episome, EBV positive clones w...
ORGANISM(S): Homo sapiens 
2013-01-22 | E-GEOD-42867 | biostudies-arrayexpress
UnknownGenerated Randomly and Selected Functionally? The Nature of Enterovirus Recombination.
Not available
S-EPMC9144335 | biostudies-literature
TranscriptomicsTranscription profiling of cerebellum from transgenic mice with nuclear and extranuclear polyQ to investigate the role of polyQ in Huntingtons disease
To dissect the impact of nuclear and extranuclear mutant htt on the initiation and progression of disease, we generated a series of transgenic mouse lines in which nuclear localization (NLS) or nuclear export sequences (NES) have been placed N-terminal to the htt exon 1 protein carrying 144 glutamin...
ORGANISM(S): Mus musculus 
2007-07-03 | E-GEOD-3248 | biostudies-arrayexpress
UnknownPhase II Trial of Atezolizumab and Bevacizumab for Treatment of HPV-Positive Unresectable or Metastatic Squamous Cell Carcinoma of the Anal Canal.
Not available
S-EPMC12010964 | biostudies-literature
UnknownNADPH Oxidase-4 Overexpression Is Associated With Epithelial Ciliary Dysfunction in Neutrophilic Asthma.
Not available
S-EPMC4893823 | biostudies-literature
UnknownCytokine Storms in COVID-19, Hemophagocytic Lymphohistiocytosis, and CAR-T Therapy.
Not available
S-EPMC11976493 | biostudies-literature
UnknownDexmedetomidine- or Clonidine-Based Sedation Compared With Propofol in Critically Ill Patients: The A2B Randomized Clinical Trial.
Not available
S-EPMC12090071 | biostudies-literature
UnknownCost-Effectiveness of α2 Agonists for Intravenous Sedation in Patients With Critical Illness.
Not available
S-EPMC12090026 | biostudies-literature
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