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TranscriptomicsInduction of interferon-stimulated genes on the IL-4 response axis by Epstein-Barr virus infected human B cells; relevance to cellular transformation.
Epstein-Barr virus (EBV) is an oncogenic virus that is associated with the pathogenesis of several human lymphoid malignancies, including Hodgkin's lymphoma. Infection of normal resting B cells with EBV results in activation to lymphoblasts that are phenotypically similar to those generated by physi...
ORGANISM(S): Homo sapiens 
2014-02-03 | E-GEOD-45829 | biostudies-arrayexpress
TranscriptomicsDown-regulation of BLIMP1-alpha by the EBV oncogene, LMP1, disrupts the plasma cell differentiation program and prevents viral replication in B cells
In this study, we have investigated the effect of BLIMP1α on gene expression, cell differentiation and pathogenesis in normal human GC B cells using a non-viral vector based system Gene expression was compared among BLIMP1α, LMP1-transfected and control vector-transfected GC B cells from two patient...
ORGANISM(S): Homo sapiens 
2011-07-26 | E-GEOD-27670 | biostudies-arrayexpress
TranscriptomicsLMP2A mediated gene expression changes in transfected CD10+ GCB cells
In this study, we have investigated the effect of LMP2A on gene expression in normal human GC B cells using a non-viral vector based system Keywords: transfection of viral oncogene in normal human B cells Gene expression was compared between LMP2A-transfected and control vector-transfected GC B cell...
ORGANISM(S): Homo sapiens 
2013-04-19 | E-GEOD-46143 | biostudies-arrayexpress
TranscriptomicsKDM6B-induced gene expression changes in transfected CD10-positive GC B cells
In this study, we have investigated the effect of lysine-specific demethylase 6B (KDM6B) on gene expression in normal human germinal center (GC) B cells using a non-viral vector-based system. Gene expression was compared between KDM6B-transfected and control vector-transfected GC B cells from three ...
ORGANISM(S): Homo sapiens 
2011-07-26 | E-GEOD-24044 | biostudies-arrayexpress
TranscriptomicsA Global View of the Oncogenic Landscape in Nasopharyngeal Carcinoma:An Integrated Analysis at the Genetic and Expression Levels
Previous studies have reported that the tumour cells of nasopharyngeal carcinoma (NPC) exhibit both recurrent chromosome abnormalities and changes in the expression of numerous genes. However, it is not known to what extent changes in the copy number of individual genes are associated with the obser...
ORGANISM(S): Homo sapiens 
2012-12-10 | E-GEOD-34573 | biostudies-arrayexpress
UnknownDietary fiber and probiotics influence the gut microbiome and melanoma immunotherapy response.
Not available
S-EPMC8970537 | biostudies-literature
UnknownEffects of empagliflozin on quality of life and healthcare use and costs in chronic kidney disease: a health economic analysis of the EMPA-KIDNEY trial.
Not available
S-EPMC12274867 | biostudies-literature
UnknownEmpagliflozin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.
Not available
S-EPMC10957483 | biostudies-literature
UnknownFrailty, Multimorbidity, and Polypharmacy: Exploratory Analyses of the Effects of Empagliflozin from the EMPA-KIDNEY Trial.
Not available
S-EPMC11390031 | biostudies-literature
UnknownHigher dose corticosteroids in hospitalised COVID-19 patients requiring ventilatory support (RECOVERY): a randomised, controlled, open-label, platform trial.
Not available
S-EPMC11872607 | biostudies-literature
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