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TranscriptomicsThe Role of PTHrP in Osteoblast Response to Microgravity: Implications for Osteoporosis Development.
Prolonged skeletal unloading through bedrest results in bone loss similar to that observed in elderly osteoporotic patients, but with an accelerated timeframe. This rapid effect on weight-bearing bones is also observed in astronauts who lose up to 2% of their bone mass per month spent in Space. Des...
ORGANISM(S): Mus musculus 
2016-08-09 | E-GEOD-78980 | biostudies-arrayexpress
TranscriptomicsProtection from obesity and diabetes by blockade of TGF-beta/Smad3 signaling
Imbalances in glucose and energy homeostasis are at the core of the worldwide epidemic of obesity and diabetes. Here, we illustrate an important role of the TGF-beta/Smad3 signaling pathway in regulating glucose and energy homeostasis. Smad3 deficient mice are protected from diet-induced obesity and...
ORGANISM(S): Mus musculus 
2011-07-12 | E-GEOD-28598 | biostudies-arrayexpress
UnknownFixed-dose capecitabine is feasible: results from a pharmacokinetic and pharmacogenetic study in metastatic breast cancer.
Not available
S-EPMC3673300 | biostudies-literature
TranscriptomicsTranscription profiling by array of mouse E15.5 FACS sorted pancreas populations based on double fluorescent reporter (Hes1GFP and Neurog3-RFP), DBA staining and Ptf1a-YFP.
In order to generate a comprehensive map of differentially expressed genes in embryonic mouse pancreas cell types on which to map results from later analyses, we first performed microarray-based gene expression profiling of purified E15.5 pancreas cell populations. We isolated GFP+RFP−DBA+, GFP+RFP+...
ORGANISM(S): Mus musculus 
2018-09-10 | E-MTAB-6891 | biostudies-arrayexpress
UnknownLrig1 controls intestinal stem-cell homeostasis by negative regulation of ErbB signalling.
Not available
S-EPMC3378643 | biostudies-literature
UnknownDevelopment of a Novel Renal Activity Index of Lupus Nephritis in Children and Young Adults.
Not available
S-EPMC4834060 | biostudies-literature
UnknownPopulation immunity to varicella in Canada: A Canadian Immunization Research Network (CIRN) study.
Not available
S-EPMC11332944 | biostudies-literature
UnknownSporadic detection of vaccine-derived poliovirus type 2 using next-generation sequencing in Canadian wastewater in August of 2022.
Not available
S-EPMC12000465 | biostudies-literature
UnknownCognitive and Electrophysiological Correlates of Working Memory Impairments in Neurofibromatosis Type 1.
Not available
S-EPMC8938373 | biostudies-literature
GenomicsData Access Committee
Data Access Committee EGAC00001000186
EGAC00001000186 | EGA
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