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MetabolomicsMetabolic profiling of rheumatoid arthritis neutrophils reveals altered energy metabolism that is not affected by JAK inhibition
Neutrophils play a key role in the pathophysiology of rheumatoid arthritis (RA) where release of ROS and proteases directly causes damage to joints and tissues. Neutrophil function is directly affected by Janus Kinase (JAK) inhibitor drugs, including tofacitinib and baricitinib, which are clinically...
2023-07-11 | MTBLS4766 | MetaboLights
GenomicsEGAS00001000775-sc-2023-03-15T11:18:45Z - samples
Candidate diagnostic variants reported into DECIPHER by 4 April 2022, annotated with clinical and automated pathogenicity assertions (see DOI: 10.1056/NEJMoa2209046). Genomic Diagnosis of Rare Pediatric Disease in the United Kingdom and Ireland, Wright et al, NEJM 2023.
EGAD00001010137 | EGA
UnknownLessons Learned by Novice Nursing Investigators When Developing and Implementing a Research Protocol.
Not available
S-EPMC9016539 | biostudies-literature
TranscriptomicsTranscriptional responses of Mycobacterium tuberculosis to lung surfactant
This study uses microarray analyses to examine gene expression profiles for Mycobacterium tuberculosis (Mtb) induced by exposure in vitro to bovine lung surfactant preparations that vary in apoprotein content: (i) whole lung surfactant (WLS) containing the complete mix of endogenous lipids and surfa...
ORGANISM(S): Mycobacterium tuberculosis 
2010-05-18 | E-GEOD-14005 | biostudies-arrayexpress
UnknownFactors associated with D-dimer levels in HIV-infected individuals.
Not available
S-EPMC3953205 | biostudies-literature
UnknownGenome Sequencing Technologies and Nursing: What Are the Roles of Nurses and Nurse Scientists?
Not available
S-EPMC5334658 | biostudies-literature
TranscriptomicsTranscription profiling of mouse macrophages infected with Leishmania major or Leishmania donovani
Murine bone marrow derived macrophages were infected with Leishmania major or Leishmania donovania promastigotes, allowed to phagocytose latex beads or not treated. Gene expression profiles were compared to identify i) the effect of Leishmania infection; ii) the differences in effects between L. maj...
ORGANISM(S): Mus musculus 
2008-02-05 | E-MEXP-1254 | biostudies-arrayexpress
ProteomicsAspirin Acetylates Thioredoxin Reductase 1 (isoform 4)
Thioredoxin Reductase 1 (isoform 4) was incubated with aspirin for 1 hour at 37 C followed by SDS PAGE. Samples were picked from SDS PAGE gel, digested with trypsin, and sent for LC-MS/MS.
ORGANISM(S): Homo sapiens (Human) 
2022-02-17 | PXD027882 | Pride
Thioredoxin reductase Acetylation Aspirin 
UnknownEffect of Jardiance on glucose uptake into astrocytomas.
Not available
S-EPMC11341586 | biostudies-literature
UnknownSuppression of β-Lactam Resistance by Aspergillomarasmine A Is Influenced by both the Metallo-β-Lactamase Target and the Antibiotic Partner.
Not available
S-EPMC7179287 | biostudies-literature
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