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TranscriptomicsRNA immunoprecipitation of GLD-1 followed by microarray analysis of the co-IP'ed mRNAs
RNA-binding proteins (RBPs) are critical regulators of gene expression and elucidating the interactions of RBPs with their RNA targets is necessary to understand how combinations of RBPs control transcriptome expression. The Quaking-related (QR) sub-family of STAR domain RBPs includes developmental ...
ORGANISM(S): Caenorhabditis elegans 
2011-02-04 | E-GEOD-21591 | biostudies-arrayexpress
ProteomicsImipridones cause cellular toxicity in human cells and bacteria by ectopic activation of the ClpP protease
Ectopic activation of the conserved ClpP protease by chemical activators causes toxicity in bacteria and human cells due to unrestrained proteolysis. The imipridone ONC201 has been ascribed multiple mechanisms of action and is currently in cancer clinical trials. To systematically investigate the ge...
ORGANISM(S): Homo sapiens (Human) Staphylococcus aureus 
2020-03-26 | PXD016119 | Pride
Imipridones Clpp protease 
Transcriptomicsbrain expression data from adult mice prenatally exposed to ethanol
Moderate alcohol consumption during pregnancy can result in a heterogeneous range of neurobehavioural and cognitive effects, termed fetal alcohol spectrum disorders (FASD). We have developed a mouse moder of FASD that involves moderate ethanol exposure throughout gestation achieved by voluntary mat...
ORGANISM(S): Mus musculus 
2011-12-10 | E-GEOD-34305 | biostudies-arrayexpress
UnknownRandomized, double-blind, placebo-controlled, phase III chemoprevention trial of selenium supplementation in patients with resected stage I non-small-cell lung cancer: ECOG 5597.
Not available
S-EPMC3821010 | biostudies-literature
ProteomicsBenchmarking and Best Practices for Quantitative Proteomics
We use an integrated benchmarking approach to empirically establish guidelines for data acquisition, statistical approach, and replicate numbers for accurate quantification. We evaluated three workflows for protein- and peptide-level quantitative accuracy: data dependent acquisition (DDA), data inde...
ORGANISM(S): Escherichia Coli (ncbitaxon:562) Homo Sapiens (ncbitaxon:9606) 
2020-04-06 | MSV000085239 | MassIVE
UnknownCultural Competency in Research: A Practical Framework for Use by Researchers, Policymakers, Community Leads and Others When Working With People From Diverse Groups.
Not available
S-EPMC12796843 | biostudies-literature
TranscriptomicsTranscription profiling of human skeletal myoblasts misexpressing myocardin
transcriptional effects of mis-expression of full length (935) myocardin in growing human skeletal myoblasts Experiment Overall Design: Compare transcriptional profiles of Ad-myocardin infected SKM5 cells with that of Ad-B-gal infected cells
ORGANISM(S): Homo sapiens 
2008-06-12 | E-GEOD-3378 | biostudies-arrayexpress
TranscriptomicsProfiling of Human Adipose Tissue and Effect of Sibutramine on Gene Expression
We analyzed the expression of 23,653 transcripts in the adipose tissue of 19 individuals treated with Sibutramine Keywords: sibutramine effect 157 adipose tissue samples from 19 individuals treated with sibutramin as well as placebo were profiled for gene expression.
ORGANISM(S): Homo sapiens 
2010-06-24 | E-GEOD-10545 | biostudies-arrayexpress
MetabolomicsGNPS-coniotin high-resolution mass spectrometry data
We purified coniotin from Coniochaeta fungus and determined its high-resolution mass (MS and MS/MS) using an Agilent 1290 Infinity II HPLC system coupled to a 6550 Q-TOF ESI/MS. Here, we deposit the full high-resolution electrospray ionization mass spectrometry data of coniotin to GNPS for public ac...
ORGANISM(S): Coniochaeta Fungus 
2025-07-14 | MSV000098505 | GNPS
GenomicsKarlsson_et_al_OSA
This experiment was conducted to generate targeted resequencing data covering a region associated with osteosarcoma in greyhounds. 8 greyhounds diagnosed with osteosarcoma and 7 greyhounds without tumors were sequenced. DNA from the 15 dogs was used to prepare libraries and hybrid capture performed ...
ORGANISM(S): Canis familiaris 
2013-11-16 | E-MTAB-1984 | biostudies-arrayexpress
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