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Aberrant activation of androgen receptor (AR)-dependent transcriptional programs is a hallmark of human prostate cancers. At the molecular level, ligand-mediated AR activation is coordinated through spatial and temporal protein-protein interactions (PPIs) involving AR-interacting proteins, which we ...
ORGANISM(S): Homo sapiens (Human) 
2016-07-20 | PXD002861 | Pride
Aberrant androgen receptor (AR)-mediated transcription is a critical driver in progression of human prostate cancer. It's known that different doses of androgens can elicit differential transcriptional and proliferative responses in prostate-tumor cells. Here, we set out to examine the androgenic re...
ORGANISM(S): Homo sapiens (Human) 
2022-03-01 | PXD002913 | Pride
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