Sort   by:  
 Page size 
MetabolomicsMetabolomics reveals impaired maturation of HDL particles in adolescents with hyperinsulinaemic androgen excess
Hyperinsulinaemic androgen excess (HIAE) in prepubertal and pubertal girls usually precedes a broader pathological phenotype in adulthood that is associated with anovulatory infertility, metabolic syndrome and type 2 diabetes. The metabolic derangements that determine these long-term health risks re...
2015-04-09 | MTBLS103 | MetaboLights
ProteomicsAndrogen receptor RIME using LNCaP cells
Rapid immunoprecipitation mass spectrometry of endogenous protein (RIME) was conducted to examine interactome of androgen receptor (AR) in LNCaP cells.
ORGANISM(S): Homo Sapiens (human) 
2021-09-10 | PXD024030 | JPOST Repository
ProteomicsThe effects of enzalutamide on androgen-dependent and androgen-independent prostate cancer cells.
To investigate the mechanisms of drug resistance and castration resistance in prostate cancer, we performed proteomic sequencing on androgen-dependent prostate cancer cells (LNCaP) and androgen-independent cells (AI) treated with enzalutamide.
ORGANISM(S): Homo Sapiens 
2024-11-26 | PXD058261 |
TranscriptomicsIdentification of novel androgen-responsive genes by sequencing of LongSAGE libraries
Background: The development and maintenance of the prostate is dependent on androgens and the androgen receptor. The androgen pathway continues to be important in prostate cancer. Here, we evaluated the transcriptome of prostate cancer cells in response to androgen using long serial analysis of gene...
ORGANISM(S): Homo sapiens 
2009-10-20 | E-GEOD-18401 | biostudies-arrayexpress
TranscriptomicsExpression data from androgen treated LNCaP cells
Androgens are required for the development of normal prostate, and they are also linked to the development of prostate cancer. We used microarrays to understand the role of androgen in an androgen dependent, androgen receptor (AR) positive human metastatic cell line, LNCaP. LNCaP cells were grown in...
ORGANISM(S): Homo sapiens 
2009-12-29 | E-GEOD-17044 | biostudies-arrayexpress
TranscriptomicsAndrogen repsonsive microRNAs
This SuperSeries is composed of the following subset Series: GSE16212: Androgen repsonsive microRNAs in LNCaP cell Lines GSE16213: Androgen repsonsive microRNAs in LAPC-4 cell lines Refer to individual Series
ORGANISM(S): Homo sapiens 
2010-06-20 | E-GEOD-16225 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human prostate samples LNCaP cell gene expression during 12 months of androgen deprivation, time series
Following androgen ablation therapy (AAT), the vast majority of prostate cancer patients develop treatment resistance with a median time of 18-24 months to disease progression. To identify molecular targets that aid in prostate cancer cell survival and contribute to the androgen independent phenotyp...
ORGANISM(S): Homo sapiens 
2008-04-07 | E-GEOD-8702 | biostudies-arrayexpress
TranscriptomicsAndrogen repsonsive microRNAs in LNCaP cell Lines
The goals of this study were to evaluate changes in microRNA expression following androgen treatment. Four treatment groups were studied: untreated and those treated with 0.1, 1.0, and 10.0 nM of synthetic androgen (R1881). Data is relative to the untreated sample.
ORGANISM(S): Homo sapiens 
2010-06-20 | E-GEOD-16212 | biostudies-arrayexpress
TranscriptomicsIdentification of an SRF- and androgen-dependent gene signature in prostate cancer
The androgen receptor (AR) is the principal target for treatment of non-organ confined prostate cancer (PCa). Systems and bioinformatics approaches suggest that considerable variation exists in the mechanisms by which AR regulates expression of effector genes and point towards a role for secondary ...
ORGANISM(S): Homo sapiens 
2011-02-28 | E-GEOD-22606 | biostudies-arrayexpress
TranscriptomicsAndrogen repsonsive microRNAs in LAPC-4 cell lines
The goals of this study were to evaluate changes in microRNA expression following androgen treatment. Four treatment groups were studied: untreated and those treated with 0.1, 1.0, and 10.0 nM of synthetic androgen (R1881). Data is relative to the untreated sample.
ORGANISM(S): Homo sapiens 
2010-06-20 | E-GEOD-16213 | biostudies-arrayexpress
Sort   by:  
 Page size