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TranscriptomicsTranscription profiling of human colorectal carcinoma-derived cell lines, p53 -/-, +/-, +/+ at 0 and 12 hrs after growth arrest
Human colorectal carcinoma-derived cell lines, p53 -/-, +/-, +/+ at 0 and 12 hrs after growth arrest.
ORGANISM(S): Homo sapiens 
2007-09-28 | E-GEOD-90 | biostudies-arrayexpress
MetabolomicsRepurposing the orphan drug nitisinone to control the transmission of African trypanosomiasis
Tsetse transmit African trypanosomiasis, which is a disease fatal to both humans and animals. A vaccine to protect against this disease does not exist so transmission control relies on eliminating tsetse populations. Although neurotoxic insecticides are the gold standard for insect control, they neg...
2021-10-06 | MTBLS2166 | MetaboLights
TranscriptomicsGene expression changes in the female zebrafish (Danio rerio) brain in response to acute exposure to methylmercury
Methylmercury (MeHg) is a potent neurotoxin and endocrine disruptor that accumulates in aquatic systems. Previous studies have shown suppression of hormone levels in both male and female fish, suggesting effects on gonadotropin regulation in the brain. We investigated the gene expression profile in ...
ORGANISM(S): Danio rerio 
2010-09-30 | E-GEOD-22662 | biostudies-arrayexpress
TranscriptomicsGlobal changes in Staphylococcus aureus gene expression in human blood provide insight into mechanisms of immune evasion and virulence
Staphylococcus aureus is a leading cause of bloodstream infections worldwide. In the United States, many of these infections are caused by a strain known as USA300. Although progress has been made, our understanding of the S. aureus molecules that promote bacteremia and survival in human blood is ...
ORGANISM(S): Staphylococcus aureus 
2011-08-25 | E-GEOD-25454 | biostudies-arrayexpress
GenomicsTEAD and YAP regulate the enhancer network of human embryonic pancreatic progenitors
The genomic regulatory programs that underlie human organogenesis are poorly understood. Human pancreas development, in particular, has pivotal implications for pancreatic regeneration, cancer, and diabetes. We have now created maps of transcripts, active enhancers, and transcription factor networks...
ORGANISM(S): Homo sapiens 
2015-04-06 | E-MTAB-3061 | biostudies-arrayexpress
TranscriptomicsHuman HEK 293T cells transfected with pEGFP-survivin gene
Transcriptional profiling of human embryonic kidney 293 cells comparing transfected control pEGFP-C1 (empty vector) with pEGFP (survivin vector). One condition experiment; survivin transfected cell as test sample vs empty vector transfected cell as reference; one dye swap replicate
ORGANISM(S): Homo sapiens 
2014-10-21 | E-GEOD-43817 | biostudies-arrayexpress
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