Wrobel John A JA

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Proteomics (2)

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Nostoc sp. PCC 7120 = FACHB-418 (2)
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pride (2)

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Breast cancer (1)

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Mass Spectrometry (2)
Affinity purification coupled with mass spectrometry proteomics (1)
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2025 (1)
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2023 (2)
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Department of Biochemistry and Biophysics University of North Carolina Chapel Hill, NC USA (1)
Department of Biochemistry and Biophysics, University of North Carolina, Chapel Hill,NC 27599,USA (1)

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Multi-omic dissection of oncogenically active epiproteomes identifies drivers of proliferative or invasive breast tumors

Here we present a functional multi-omics method, interaction-Correlated Multi-omic Aberration Patterning or iC-MAP, which dissects intra-tumor heterogeneity and identifies in situ in real time the oncogenic consequences of multi-omics aberrations that drive proliferative/invasive tumor in individual...

ORGANISM(S): Homo sapiens (Human)

2019-07-26 | PXD013795 | Pride

Targeting G9a Regulated m6A Modification Pathway to Hinder SARS-CoV-2 Replication

N6-methyladenosine (m6A) modification pathway is hijacked by several RNA viruses, including SARS-CoV-2, making it an attractive host-directed target for development of broad-spectrum antivirals. Here, we show that histone methyltransferase G9a, through its interaction with METTL3, regulates SARS-CoV...

ORGANISM(S): Homo sapiens (Human)

2025-04-14 | PXD058743 | Pride

Covid-19 Sars-cov-2

SARS-CoV-2 Omicron-B.1.1.529 leads to widespread escape from neutralizing antibody responses.

Not available

S-EPMC8723827 | biostudies-literature

A second update on mapping the human genetic architecture of COVID-19.

Not available

S-EPMC10482689 | biostudies-literature

Coronary-Artery Bypass Surgery in Patients with Ischemic Cardiomyopathy.

Not available

S-EPMC4938005 | biostudies-literature