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UnknownActivation of Rab8 guanine nucleotide exchange factor Rabin8 by ERK1/2 in response to EGF signaling.
Not available
S-EPMC4291672 | biostudies-literature
UnknownExosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response.
Not available
S-EPMC6095740 | biostudies-literature
UnknownHRS phosphorylation drives immunosuppressive exosome secretion and restricts CD8+ T-cell infiltration into tumors.
Not available
S-EPMC9283393 | biostudies-literature
ProteomicsLabel-free proteome analysis of small extracellular vesicles (sEV) expressing different HRS mutants.
Label-free proteome analysis of small extracellular vesicles (sEV) derived from WM9 cells expressing different HRS mutants: wild type (HRSWT), phospho-deficient (HRSS345A), and phospho-mimetic mutant HRS (HRSS345D).
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-02-16 | MSV000088846 | MassIVE
UnknownOncogenic BRAF-Mediated Melanoma Cell Invasion.
Not available
S-EPMC4889462 | biostudies-literature
Proteomicspp6 is recruited in TNFalpha induced complex I
We identify pp6 is recruited in complex I induced by TNFalpha.
ORGANISM(S): Mus Musculus 
2021-12-14 | PXD030377 |
UnknownUpregulation of exosome secretion from tumor-associated macrophages plays a key role in the suppression of anti-tumor immunity.
Not available
S-EPMC10697782 | biostudies-literature
ProteomicsDiscovery of a cooperative mode of inhibiting RIPK1 kinase
By using Limited Proteolysis-Mass Spectrometry (LiP-MS) and Hydrogen Deuterium Exchange-Mass Spectrometry (HDX-MS) analysis, we identified the binding pocket of Nec-34 in RIPK1 kinase domain. This newly identified binding pocket of Nec-34 is distinct from distinct from that of Nec-1s.
ORGANISM(S): Homo Sapiens 
2021-03-07 | PXD024560 |
ProteomicsDiscovery of a cooperative mode of inhibiting RIPK1
We identified a peptide of RIPK1 binding with compound Nec-34
ORGANISM(S): Homo Sapiens 
2021-03-04 | PXD024534 |
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