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Sonic hedgehog (Shh) signaling plays a critical role in regulating cerebellum development by maintaining the physiological proliferation of granule neuron precursors (GNPs), and its dysregulation leads to the oncogenesis of medulloblastoma. O-GlcNAcylation (O-GlcNAc) of proteins is an emerging regul...
ORGANISM(S): Homo Sapiens 
Data Access Committee EGAC00001000627
Data Access Committee EGAC00001000070
The total protein in the sample was extracted, part of the sample was taken out for protein concentration determination and SDS-PAGE detection, the other part was taken out for trypsin enzymolysis and labeling, and then equal amount of each labeled sample was mixed for chromatographic separation. Fi...
ORGANISM(S): Mus Musculus 
2023-02-09 | PXD040011 |
By precisely dissected MS for proteomics, we found that donepezil remarkably restored (at high dose), even elevated (at low dose) the level of vacuolar protein sorting-associated protein 37D (VP37D), an autophagy-related protein, in hTauMS mice.
ORGANISM(S): Mus musculus (Mouse) 
2021-09-09 | PXD023297 | Pride
Data from ProteomeXchange, PXD ID: PXD001246. File: GLY_M11_20140408.mzml. Published as part of Mol Cell Proteomics. 2014 Dec 13 . From the Abstract: {{i}} Large scale quantitative evaluation of the tightness of membrane association for non-transmembrane proteins is important for identifying true p...
ORGANISM(S): Synechococcus_phage_p60_uid14628, Synechococcus_phage_syn5_uid19763, Synechococcus_phage_syn9_uid17541, Synechococcus_phage_s_pm2_uid15223, Synechococcus_phage_s_rsm4_uid39923, Synechocystis_pcc_6803 
The differentiation of distinct multifocal hepatocellular carcinoma (HCC): multicentric disease vs. intrahepatic metastases, in which the management and prognosis varies substantively, remains problematic. We aim to stratify multifocal HCC and identify novel diagnostic and prognostic biomarkers by p...
Poly A transcriptome sequence of mutifocal hepatocelular carcinoma
Background & Aims: The differentiation of distinct multifocal hepatocellular carcinoma (HCC): multicentric disease vs. intrahepatic metastases, in which the management and prognosis varies substantively, remains problematic. We aim to stratify multifocal HCC and identify novel diagnostic and prognos...
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